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Page 1
Growth factor receptor binding protein 14 inhibition triggers insulin-induced mouse hepatocyte proliferation and is associated with hepatocellular carcinoma.
Morzyglod L, Caüzac M, Popineau L, Denechaud PD, Fajas L, Ragazzon B, Fauveau V, Planchais J, Vasseur-Cognet M, Fartoux L, Scatton O, Rosmorduc O, Guilmeau S, Postic C, Desdouets C, Desbois-Mouthon C, Burnol AF. Morzyglod L, et al. Among authors: fajas l. Hepatology. 2017 Apr;65(4):1352-1368. doi: 10.1002/hep.28972. Epub 2017 Feb 21. Hepatology. 2017. PMID: 27981611
E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis.
Denechaud PD, Lopez-Mejia IC, Giralt A, Lai Q, Blanchet E, Delacuisine B, Nicolay BN, Dyson NJ, Bonner C, Pattou F, Annicotte JS, Fajas L. Denechaud PD, et al. Among authors: fajas l. J Clin Invest. 2016 Jan;126(1):137-50. doi: 10.1172/JCI81542. Epub 2015 Nov 30. J Clin Invest. 2016. PMID: 26619117 Free PMC article.
CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. Among authors: fajas l. J Clin Invest. 2016 Jan;126(1):335-48. doi: 10.1172/JCI81480. Epub 2015 Dec 14. J Clin Invest. 2016. Retraction in: J Clin Invest. 2023 Mar 15;133(6):e170315. doi: 10.1172/JCI170315 PMID: 26657864 Free PMC article. Retracted.
KAT2B Is Required for Pancreatic Beta Cell Adaptation to Metabolic Stress by Controlling the Unfolded Protein Response.
Rabhi N, Denechaud PD, Gromada X, Hannou SA, Zhang H, Rashid T, Salas E, Durand E, Sand O, Bonnefond A, Yengo L, Chavey C, Bonner C, Kerr-Conte J, Abderrahmani A, Auwerx J, Fajas L, Froguel P, Annicotte JS. Rabhi N, et al. Among authors: fajas l. Cell Rep. 2016 May 3;15(5):1051-1061. doi: 10.1016/j.celrep.2016.03.079. Epub 2016 Apr 21. Cell Rep. 2016. PMID: 27117420 Free article.
CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.
Lopez-Mejia IC, Lagarrigue S, Giralt A, Martinez-Carreres L, Zanou N, Denechaud PD, Castillo-Armengol J, Chavey C, Orpinell M, Delacuisine B, Nasrallah A, Collodet C, Zhang L, Viollet B, Hardie DG, Fajas L. Lopez-Mejia IC, et al. Among authors: fajas l. Mol Cell. 2017 Oct 19;68(2):336-349.e6. doi: 10.1016/j.molcel.2017.09.034. Mol Cell. 2017. PMID: 29053957 Free article.
E2F1, a Novel Regulator of Metabolism.
Denechaud PD, Fajas L, Giralt A. Denechaud PD, et al. Among authors: fajas l. Front Endocrinol (Lausanne). 2017 Nov 10;8:311. doi: 10.3389/fendo.2017.00311. eCollection 2017. Front Endocrinol (Lausanne). 2017. PMID: 29176962 Free PMC article. Review.
118 results