Sagi I - Search Results

1

Harnessing the natural inhibitory domain to control TNFα Converting Enzyme (TACE) activity in vivo.

Wong E, Cohen T, Romi E, Levin M, Peleg Y, Arad U, Yaron A, Milla ME, Sagi I. Wong E, et al. Among authors: sagi i. Sci Rep. 2016 Dec 16;6:35598. doi: 10.1038/srep35598. Sci Rep. 2016. PMID: 27982031 Free PMC article.

2

Inhibition of the tumor necrosis factor-alpha-converting enzyme by its pro domain.

Gonzales PE, Solomon A, Miller AB, Leesnitzer MA, Sagi I, Milla ME. Gonzales PE, et al. Among authors: sagi i. J Biol Chem. 2004 Jul 23;279(30):31638-45. doi: 10.1074/jbc.M401311200. Epub 2004 Apr 20. J Biol Chem. 2004. PMID: 15100227 Free article.

3

Pronounced diversity in electronic and chemical properties between the catalytic zinc sites of tumor necrosis factor-alpha-converting enzyme and matrix metalloproteinases despite their high structural similarity.

Solomon A, Rosenblum G, Gonzales PE, Leonard JD, Mobashery S, Milla ME, Sagi I. Solomon A, et al. Among authors: sagi i. J Biol Chem. 2004 Jul 23;279(30):31646-54. doi: 10.1074/jbc.M401310200. Epub 2004 Apr 21. J Biol Chem. 2004. PMID: 15102849 Free article.

4

Key feature of the catalytic cycle of TNF-alpha converting enzyme involves communication between distal protein sites and the enzyme catalytic core.

Solomon A, Akabayov B, Frenkel A, Milla ME, Sagi I. Solomon A, et al. Among authors: sagi i. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):4931-6. doi: 10.1073/pnas.0700066104. Epub 2007 Mar 13. Proc Natl Acad Sci U S A. 2007. PMID: 17360351 Free PMC article.

5

Application of structural dynamic approaches provide novel insights into the enzymatic mechanism of the tumor necrosis factor-alpha-converting enzyme.

Sagi I, Milla ME. Sagi I, et al. Anal Biochem. 2008 Jan 1;372(1):1-10. doi: 10.1016/j.ab.2007.07.037. Epub 2007 Sep 26. Anal Biochem. 2008. PMID: 17963710 Free PMC article. Review.

6

ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A.

Romi E, Gokhman I, Wong E, Antonovsky N, Ludwig A, Sagi I, Saftig P, Tessier-Lavigne M, Yaron A. Romi E, et al. Among authors: sagi i. Nat Commun. 2014 Jun 5;5:4058. doi: 10.1038/ncomms5058. Nat Commun. 2014. PMID: 24898499 Free article.

7

Introduction of correlative light and airSEM™ microscopy imaging for tissue research under ambient conditions.

Solomonov I, Talmi-Frank D, Milstein Y, Addadi S, Aloshin A, Sagi I. Solomonov I, et al. Among authors: sagi i. Sci Rep. 2014 Aug 7;4:5987. doi: 10.1038/srep05987. Sci Rep. 2014. PMID: 25100357 Free PMC article.

8

The Functional Maturation of A Disintegrin and Metalloproteinase (ADAM) 9, 10, and 17 Requires Processing at a Newly Identified Proprotein Convertase (PC) Cleavage Site.

Wong E, Maretzky T, Peleg Y, Blobel CP, Sagi I. Wong E, et al. Among authors: sagi i. J Biol Chem. 2015 May 8;290(19):12135-46. doi: 10.1074/jbc.M114.624072. Epub 2015 Mar 20. J Biol Chem. 2015. PMID: 25795784 Free PMC article.

9

PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells.

Gur-Cohen S, Itkin T, Chakrabarty S, Graf C, Kollet O, Ludin A, Golan K, Kalinkovich A, Ledergor G, Wong E, Niemeyer E, Porat Z, Erez A, Sagi I, Esmon CT, Ruf W, Lapidot T. Gur-Cohen S, et al. Among authors: sagi i. Nat Med. 2015 Nov;21(11):1307-17. doi: 10.1038/nm.3960. Epub 2015 Oct 12. Nat Med. 2015. PMID: 26457757 Free PMC article.

10

Cytokine secretion and NK cell activity in human ADAM17 deficiency.

Tsukerman P, Eisenstein EM, Chavkin M, Schmiedel D, Wong E, Werner M, Yaacov B, Averbuch D, Molho-Pessach V, Stepensky P, Kaynan N, Bar-On Y, Seidel E, Yamin R, Sagi I, Elpeleg O, Mandelboim O. Tsukerman P, et al. Among authors: sagi i. Oncotarget. 2015 Dec 29;6(42):44151-60. doi: 10.18632/oncotarget.6629. Oncotarget. 2015. PMID: 26683521 Free PMC article.

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