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Dual ALK and CDK4/6 Inhibition Demonstrates Synergy against Neuroblastoma.
Wood AC, Krytska K, Ryles HT, Infarinato NR, Sano R, Hansel TD, Hart LS, King FJ, Smith TR, Ainscow E, Grandinetti KB, Tuntland T, Kim S, Caponigro G, He YQ, Krupa S, Li N, Harris JL, Mossé YP. Wood AC, et al. Among authors: ainscow e. Clin Cancer Res. 2017 Jun 1;23(11):2856-2868. doi: 10.1158/1078-0432.CCR-16-1114. Epub 2016 Dec 16. Clin Cancer Res. 2017. PMID: 27986745 Free PMC article.
A Fully Automated High-Throughput Flow Cytometry Screening System Enabling Phenotypic Drug Discovery.
Joslin J, Gilligan J, Anderson P, Garcia C, Sharif O, Hampton J, Cohen S, King M, Zhou B, Jiang S, Trussell C, Dunn R, Fathman JW, Snead JL, Boitano AE, Nguyen T, Conner M, Cooke M, Harris J, Ainscow E, Zhou Y, Shaw C, Sipes D, Mainquist J, Lesley S. Joslin J, et al. Among authors: ainscow e. SLAS Discov. 2018 Aug;23(7):697-707. doi: 10.1177/2472555218773086. Epub 2018 May 29. SLAS Discov. 2018. PMID: 29843542 Free PMC article.
A Phase I Trial of CT900, a Novel α-Folate Receptor-Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer.
Banerjee S, Michalarea V, Ang JE, Ingles Garces A, Biondo A, Funingana IG, Little M, Ruddle R, Raynaud F, Riisnaes R, Gurel B, Chua S, Tunariu N, Porter JC, Prout T, Parmar M, Zachariou A, Turner A, Jenkins B, McIntosh S, Ainscow E, Minchom A, Lopez J, de Bono J, Jones R, Hall E, Cook N, Basu B, Banerji U. Banerjee S, et al. Among authors: ainscow e. Clin Cancer Res. 2022 Nov 1;28(21):4634-4641. doi: 10.1158/1078-0432.CCR-22-1268. Clin Cancer Res. 2022. PMID: 35984704 Free PMC article. Clinical Trial.
Suppressors of superoxide production from mitochondrial complex III.
Orr AL, Vargas L, Turk CN, Baaten JE, Matzen JT, Dardov VJ, Attle SJ, Li J, Quackenbush DC, Goncalves RL, Perevoshchikova IV, Petrassi HM, Meeusen SL, Ainscow EK, Brand MD. Orr AL, et al. Among authors: ainscow ek. Nat Chem Biol. 2015 Nov;11(11):834-6. doi: 10.1038/nchembio.1910. Epub 2015 Sep 14. Nat Chem Biol. 2015. PMID: 26368590 Free PMC article.
Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.
Brand MD, Goncalves RL, Orr AL, Vargas L, Gerencser AA, Borch Jensen M, Wang YT, Melov S, Turk CN, Matzen JT, Dardov VJ, Petrassi HM, Meeusen SL, Perevoshchikova IV, Jasper H, Brookes PS, Ainscow EK. Brand MD, et al. Among authors: ainscow ek. Cell Metab. 2016 Oct 11;24(4):582-592. doi: 10.1016/j.cmet.2016.08.012. Epub 2016 Sep 22. Cell Metab. 2016. PMID: 27667666 Free PMC article.
Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes.
Ainscow EK, Brand MD. Ainscow EK, et al. Eur J Biochem. 1999 Dec;266(3):737-49. doi: 10.1046/j.1432-1327.1999.00856.x. Eur J Biochem. 1999. PMID: 10583367 Free article.
Previously [Ainscow, E.K. & Brand, M.D. (1999) Eur. J. Biochem. 263, 671-685], top-down control analysis was used to describe the control pattern of energy metabolism in rat hepatocytes. ...
Previously [Ainscow, E.K. & Brand, M.D. (1999) Eur. J. Biochem. 263, 671-685], top-down control analysis was used to descr …
36 results