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The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction.
Schwabl P, Hambruch E, Seeland BA, Hayden H, Wagner M, Garnys L, Strobel B, Schubert TL, Riedl F, Mitteregger D, Burnet M, Starlinger P, Oberhuber G, Deuschle U, Rohr-Udilova N, Podesser BK, Peck-Radosavljevic M, Reiberger T, Kremoser C, Trauner M. Schwabl P, et al. Among authors: trauner m. J Hepatol. 2017 Apr;66(4):724-733. doi: 10.1016/j.jhep.2016.12.005. Epub 2016 Dec 18. J Hepatol. 2017. PMID: 27993716 Free article.
New molecular insights into the mechanisms of cholestasis.
Wagner M, Zollner G, Trauner M. Wagner M, et al. Among authors: trauner m. J Hepatol. 2009 Sep;51(3):565-80. doi: 10.1016/j.jhep.2009.05.012. Epub 2009 May 28. J Hepatol. 2009. PMID: 19595470 Free article. Review.
Nuclear receptors in liver disease.
Wagner M, Zollner G, Trauner M. Wagner M, et al. Among authors: trauner m. Hepatology. 2011 Mar;53(3):1023-34. doi: 10.1002/hep.24148. Epub 2011 Feb 11. Hepatology. 2011. PMID: 21319202 Review.
Will we ever model PSC? - "it's hard to be a PSC model!".
Pollheimer MJ, Trauner M, Fickert P. Pollheimer MJ, et al. Among authors: trauner m. Clin Res Hepatol Gastroenterol. 2011 Dec;35(12):792-804. doi: 10.1016/j.clinre.2011.04.014. Epub 2011 Jun 23. Clin Res Hepatol Gastroenterol. 2011. PMID: 21703962 Review.
Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output.
Baghdasaryan A, Claudel T, Gumhold J, Silbert D, Adorini L, Roda A, Vecchiotti S, Gonzalez FJ, Schoonjans K, Strazzabosco M, Fickert P, Trauner M. Baghdasaryan A, et al. Among authors: trauner m. Hepatology. 2011 Oct;54(4):1303-12. doi: 10.1002/hep.24537. Hepatology. 2011. PMID: 22006858 Free PMC article.
The interaction of hepatic lipid and glucose metabolism in liver diseases.
Bechmann LP, Hannivoort RA, Gerken G, Hotamisligil GS, Trauner M, Canbay A. Bechmann LP, et al. Among authors: trauner m. J Hepatol. 2012 Apr;56(4):952-64. doi: 10.1016/j.jhep.2011.08.025. Epub 2011 Dec 13. J Hepatol. 2012. PMID: 22173168 Free article. Review.
816 results