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Genotoxic risk of ethyl-paraben could be related to telomere shortening.
Finot F, Kaddour A, Morat L, Mouche I, Zaguia N, Cuceu C, Souverville D, Négrault S, Cariou O, Essahli A, Prigent N, Saul J, Paillard F, Heidingsfelder L, Lafouge P, Al Jawhari M, Hempel WM, El May M, Colicchio B, Dieterlen A, Jeandidier E, Sabatier L, Clements J, M'Kacher R. Finot F, et al. Among authors: cariou o. J Appl Toxicol. 2017 Jun;37(6):758-771. doi: 10.1002/jat.3425. Epub 2016 Dec 20. J Appl Toxicol. 2017. PMID: 27995640
A new tool for genotoxic risk assessment: Reevaluation of the cytokinesis-block micronucleus assay using semi-automated scoring following telomere and centromere staining.
Zaguia N, Laplagne E, Colicchio B, Cariou O, Al Jawhari M, Heidingsfelder L, Hempel WM, Jrad BBH, Jeandidier E, Dieterlen A, Carde P, Voisin P, M'kacher R. Zaguia N, et al. Among authors: cariou o. Mutat Res Genet Toxicol Environ Mutagen. 2020 Feb-Mar;850-851:503143. doi: 10.1016/j.mrgentox.2020.503143. Epub 2020 Jan 22. Mutat Res Genet Toxicol Environ Mutagen. 2020. PMID: 32247554
Cytosine arabinoside, vinblastine, 5-fluorouracil and 2-aminoanthracene testing in the in vitro micronucleus assay with L5178Y mouse lymphoma cells at Sanofi Aventis, with different cytotoxicity measurements, in support of the draft OECD Test Guideline on In Vitro Mammalian Cell Micronucleus Test.
Cariou O, Laroche-Prigent N, Ledieu S, Guizon I, Paillard F, Thybaud V. Cariou O, et al. Mutat Res. 2010 Oct 29;702(2):148-56. doi: 10.1016/j.mrgentox.2010.04.005. Epub 2010 Apr 14. Mutat Res. 2010. PMID: 20398790