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Page 1
Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases.
Hinks A, Bowes J, Cobb J, Ainsworth HC, Marion MC, Comeau ME, Sudman M, Han B; Juvenile Arthritis Consortium for Immunochip; Becker ML, Bohnsack JF, de Bakker PI, Haas JP, Hazen M, Lovell DJ, Nigrovic PA, Nordal E, Punnaro M, Rosenberg AM, Rygg M, Smith SL, Wise CA, Videm V, Wedderburn LR, Yarwood A, Yeung RS, Prahalad S, Langefeld CD, Raychaudhuri S, Thompson SD, Thomson W. Hinks A, et al. Among authors: de bakker pi. Ann Rheum Dis. 2017 Apr;76(4):765-772. doi: 10.1136/annrheumdis-2016-210025. Epub 2016 Dec 20. Ann Rheum Dis. 2017. PMID: 27998952 Free PMC article.
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis.
Raychaudhuri S, Sandor C, Stahl EA, Freudenberg J, Lee HS, Jia X, Alfredsson L, Padyukov L, Klareskog L, Worthington J, Siminovitch KA, Bae SC, Plenge RM, Gregersen PK, de Bakker PI. Raychaudhuri S, et al. Among authors: de bakker pi. Nat Genet. 2012 Jan 29;44(3):291-6. doi: 10.1038/ng.1076. Nat Genet. 2012. PMID: 22286218 Free PMC article.
Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans.
McLaren PJ, Ripke S, Pelak K, Weintrob AC, Patsopoulos NA, Jia X, Erlich RL, Lennon NJ, Kadie CM, Heckerman D, Gupta N, Haas DW, Deeks SG, Pereyra F, Walker BD, de Bakker PI; International HIV Controllers Study. McLaren PJ, et al. Among authors: de bakker pi. Hum Mol Genet. 2012 Oct 1;21(19):4334-47. doi: 10.1093/hmg/dds226. Epub 2012 Jun 19. Hum Mol Genet. 2012. PMID: 22718199 Free PMC article.
Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.
Morris DL, Taylor KE, Fernando MM, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G; International MHC and Autoimmunity Genetics Network; Langefeld CD, Noble JA, Rioux JD, Seldin MF; Systemic Lupus Erythematosus Genetics Consortium; Criswell LA, Vyse TJ. Morris DL, et al. Am J Hum Genet. 2012 Nov 2;91(5):778-93. doi: 10.1016/j.ajhg.2012.08.026. Epub 2012 Oct 18. Am J Hum Genet. 2012. PMID: 23084292 Free PMC article.
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E, Viatte S, McAllister K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C, Trynka G, Franke L, Westra HJ, Alfredsson L, Hu X, Sandor C, de Bakker PI, Davila S, Khor CC, Heng KK, Andrews R, Edkins S, Hunt SE, Langford C, Symmons D; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate; Wellcome Trust Case Control Consortium; Concannon P, Onengut-Gumuscu S, Rich SS, Deloukas P, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Ärlsetig L, Martin J, Rantapää-Dahlqvist S, Plenge RM, Raychaudhuri S, Klareskog L, Gregersen PK, Worthington J. Eyre S, et al. Among authors: de bakker pi. Nat Genet. 2012 Dec;44(12):1336-40. doi: 10.1038/ng.2462. Epub 2012 Nov 11. Nat Genet. 2012. PMID: 23143596 Free PMC article.
Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.
Xie G, Roshandel D, Sherva R, Monach PA, Lu EY, Kung T, Carrington K, Zhang SS, Pulit SL, Ripke S, Carette S, Dellaripa PF, Edberg JC, Hoffman GS, Khalidi N, Langford CA, Mahr AD, St Clair EW, Seo P, Specks U, Spiera RF, Stone JH, Ytterberg SR, Raychaudhuri S, de Bakker PI, Farrer LA, Amos CI, Merkel PA, Siminovitch KA. Xie G, et al. Among authors: de bakker pi. Arthritis Rheum. 2013 Sep;65(9):2457-68. doi: 10.1002/art.38036. Arthritis Rheum. 2013. PMID: 23740775 Free PMC article.
Imputing amino acid polymorphisms in human leukocyte antigens.
Jia X, Han B, Onengut-Gumuscu S, Chen WM, Concannon PJ, Rich SS, Raychaudhuri S, de Bakker PI. Jia X, et al. Among authors: de bakker pi. PLoS One. 2013 Jun 6;8(6):e64683. doi: 10.1371/journal.pone.0064683. Print 2013. PLoS One. 2013. PMID: 23762245 Free PMC article.
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects.
Patsopoulos NA, Barcellos LF, Hintzen RQ, Schaefer C, van Duijn CM, Noble JA, Raj T; IMSGC; ANZgene; Gourraud PA, Stranger BE, Oksenberg J, Olsson T, Taylor BV, Sawcer S, Hafler DA, Carrington M, De Jager PL, de Bakker PI. Patsopoulos NA, et al. Among authors: de jager pl, de bakker pi. PLoS Genet. 2013 Nov;9(11):e1003926. doi: 10.1371/journal.pgen.1003926. Epub 2013 Nov 21. PLoS Genet. 2013. PMID: 24278027 Free PMC article.
284 results