Miyazawa T - Search Results

1

A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units.

Ray L, Valentic TR, Miyazawa T, Withall DM, Song L, Milligan JC, Osada H, Takahashi S, Tsai SC, Challis GL. Ray L, et al. Among authors: miyazawa t. Nat Commun. 2016 Dec 21;7:13609. doi: 10.1038/ncomms13609. Nat Commun. 2016. PMID: 28000660 Free PMC article.

2

Structure-function analyses of cytochrome P450revI involved in reveromycin A biosynthesis and evaluation of the biological activity of its substrate, reveromycin T.

Takahashi S, Nagano S, Nogawa T, Kanoh N, Uramoto M, Kawatani M, Shimizu T, Miyazawa T, Shiro Y, Osada H. Takahashi S, et al. Among authors: miyazawa t. J Biol Chem. 2014 Nov 21;289(47):32446-58. doi: 10.1074/jbc.M114.598391. Epub 2014 Sep 25. J Biol Chem. 2014. PMID: 25258320 Free PMC article.

3

Identification of Middle Chain Fatty Acyl-CoA Ligase Responsible for the Biosynthesis of 2-Alkylmalonyl-CoAs for Polyketide Extender Unit.

Miyazawa T, Takahashi S, Kawata A, Panthee S, Hayashi T, Shimizu T, Nogawa T, Osada H. Miyazawa T, et al. J Biol Chem. 2015 Nov 6;290(45):26994-27011. doi: 10.1074/jbc.M115.677195. Epub 2015 Sep 16. J Biol Chem. 2015. PMID: 26378232 Free PMC article.

4

An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s.

Kanoh N, Kawamata-Asano A, Suzuki K, Takahashi Y, Miyazawa T, Nakamura T, Moriya T, Hirano H, Osada H, Iwabuchi Y, Takahashi S. Kanoh N, et al. Among authors: miyazawa t. Sci Rep. 2019 Dec 2;9(1):18023. doi: 10.1038/s41598-019-54473-8. Sci Rep. 2019. PMID: 31792277 Free PMC article.

5

An in vitro platform for engineering and harnessing modular polyketide synthases.

Miyazawa T, Hirsch M, Zhang Z, Keatinge-Clay AT. Miyazawa T, et al. Nat Commun. 2020 Jan 3;11(1):80. doi: 10.1038/s41467-019-13811-0. Nat Commun. 2020. PMID: 31900404 Free PMC article.

6

Assessing and harnessing updated polyketide synthase modules through combinatorial engineering.

Ray KA, Lutgens JD, Bista R, Zhang J, Desai RR, Hirsch M, Miyazawa T, Cordova A, Keatinge-Clay AT. Ray KA, et al. Among authors: miyazawa t. Nat Commun. 2024 Aug 1;15(1):6485. doi: 10.1038/s41467-024-50844-6. Nat Commun. 2024. PMID: 39090122 Free PMC article.

7

Insights into modular polyketide synthase loops aided by repetitive sequences.

Hirsch M, Kumru K, Desai RR, Fitzgerald BJ, Miyazawa T, Ray KA, Saif N, Spears S, Keatinge-Clay AT. Hirsch M, et al. Among authors: miyazawa t. Proteins. 2021 Sep;89(9):1099-1110. doi: 10.1002/prot.26083. Epub 2021 Apr 28. Proteins. 2021. PMID: 33843112 Free PMC article.

8

Priming enzymes from the pikromycin synthase reveal how assembly-line ketosynthases catalyze carbon-carbon chemistry.

Dickinson MS, Miyazawa T, McCool RS, Keatinge-Clay AT. Dickinson MS, et al. Among authors: miyazawa t. Structure. 2022 Sep 1;30(9):1331-1339.e3. doi: 10.1016/j.str.2022.05.021. Epub 2022 Jun 22. Structure. 2022. PMID: 35738283 Free PMC article.

9

The Bacillus subtilis essential gene dgkB is dispensable in mutants with defective lipoteichoic acid synthesis.

Matsuoka S, Hashimoto M, Kamiya Y, Miyazawa T, Ishikawa K, Hara H, Matsumoto K. Matsuoka S, et al. Among authors: miyazawa t. Genes Genet Syst. 2011;86(6):365-76. doi: 10.1266/ggs.86.365. Genes Genet Syst. 2011. PMID: 22451476 Free article.

10

Preparative production of an enantiomeric pair by engineered polyketide synthases.

Miyazawa T , Fitzgerald BJ , Keatinge-Clay AT . Miyazawa T , et al. Chem Commun (Camb). 2021 Sep 11;57(70):8762-8765. doi: 10.1039/d1cc03073f. Epub 2021 Aug 11. Chem Commun (Camb). 2021. PMID: 34378565 Free PMC article.

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