Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes.
Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Hodder PS, Rosen H, Cravatt BF.
Adibekian A, et al.
J Am Chem Soc. 2012 Jun 27;134(25):10345-8. doi: 10.1021/ja303400u. Epub 2012 Jun 12.
J Am Chem Soc. 2012.
PMID: 22690931
Free PMC article.