Rubin J - Search Results

1

Assessment of safety and efficacy of long-term treatment with combination lumacaftor and ivacaftor therapy in patients with cystic fibrosis homozygous for the F508del-CFTR mutation (PROGRESS): a phase 3, extension study.

Konstan MW, McKone EF, Moss RB, Marigowda G, Tian S, Waltz D, Huang X, Lubarsky B, Rubin J, Millar SJ, Pasta DJ, Mayer-Hamblett N, Goss CH, Morgan W, Sawicki GS. Konstan MW, et al. Among authors: rubin j. Lancet Respir Med. 2017 Feb;5(2):107-118. doi: 10.1016/S2213-2600(16)30427-1. Epub 2016 Dec 21. Lancet Respir Med. 2017. PMID: 28011037 Clinical Trial.

2

Frequency and costs of pulmonary exacerbations in patients with cystic fibrosis in the United States.

Rubin JL, Thayer S, Watkins A, Wagener JS, Hodgkins PS, Schechter MS. Rubin JL, et al. Curr Med Res Opin. 2017 Apr;33(4):667-674. doi: 10.1080/03007995.2016.1277196. Epub 2017 Feb 9. Curr Med Res Opin. 2017. PMID: 28058864

3

Lumacaftor/Ivacaftor reduces pulmonary exacerbations in patients irrespective of initial changes in FEV₁.

McColley SA, Konstan MW, Ramsey BW, Stuart Elborn J, Boyle MP, Wainwright CE, Waltz D, Vera-Llonch M, Marigowda G, Jiang JG, Rubin JL. McColley SA, et al. Among authors: rubin jl. J Cyst Fibros. 2019 Jan;18(1):94-101. doi: 10.1016/j.jcf.2018.07.011. Epub 2018 Aug 23. J Cyst Fibros. 2019. PMID: 30146268 Free PMC article. Clinical Trial.

4

Modeling long-term health outcomes of patients with cystic fibrosis homozygous for F508del-CFTR treated with lumacaftor/ivacaftor.

Rubin JL, O'Callaghan L, Pelligra C, Konstan MW, Ward A, Ishak JK, Chandler C, Liou TG. Rubin JL, et al. Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466618820186. doi: 10.1177/1753466618820186. Ther Adv Respir Dis. 2019. PMID: 30803355 Free PMC article.

5

Long-term safety and efficacy of tezacaftor-ivacaftor in individuals with cystic fibrosis aged 12 years or older who are homozygous or heterozygous for Phe508del CFTR (EXTEND): an open-label extension study.

Flume PA, Biner RF, Downey DG, Brown C, Jain M, Fischer R, De Boeck K, Sawicki GS, Chang P, Paz-Diaz H, Rubin JL, Yang Y, Hu X, Pasta DJ, Millar SJ, Campbell D, Wang X, Ahluwalia N, Owen CA, Wainwright CE; VX14-661-110 study group. Flume PA, et al. Among authors: rubin jl. Lancet Respir Med. 2021 Jul;9(7):733-746. doi: 10.1016/S2213-2600(20)30510-5. Epub 2021 Feb 10. Lancet Respir Med. 2021. PMID: 33581080

6

Healthcare resource utilization and costs among children with cystic fibrosis in the United States.

Thorat T, McGarry LJ, Bonafede MM, Limone BL, Rubin JL, Jariwala-Parikh K, Konstan MW. Thorat T, et al. Among authors: rubin jl. Pediatr Pulmonol. 2021 Sep;56(9):2833-2844. doi: 10.1002/ppul.25535. Epub 2021 Jul 7. Pediatr Pulmonol. 2021. PMID: 34138523 Free PMC article.

7

A Retrospective, Longitudinal Registry Study on the Long-Term Durability of Ivacaftor Treatment in People with Cystic Fibrosis.

Merlo C, Thorat T, McGarry LJ, Scirica CV, DerSarkissian M, Nguyen C, Gu YM, Muthukumar A, Healy J, Rubin JL, Brookhart MA. Merlo C, et al. Among authors: rubin jl. Pulm Ther. 2024 Sep 12. doi: 10.1007/s41030-024-00269-9. Online ahead of print. Pulm Ther. 2024. PMID: 39266929 Free article.

8

Limitations of standard cost-effectiveness methods for health technology assessment of treatments for rare, chronic diseases: a case study of treatment for cystic fibrosis.

Rubin JL, Lopez A, Booth J, Gunther P, Jena AB. Rubin JL, et al. J Med Econ. 2022 Jan-Dec;25(1):783-791. doi: 10.1080/13696998.2022.2077550. J Med Econ. 2022. PMID: 35549639 Free article.

9

Elexacaftor/tezacaftor/ivacaftor projected survival and long-term health outcomes in people with cystic fibrosis homozygous for F508del.

Lopez A, Daly C, Vega-Hernandez G, MacGregor G, Rubin JL. Lopez A, et al. J Cyst Fibros. 2023 Jul;22(4):607-614. doi: 10.1016/j.jcf.2023.02.004. Epub 2023 Feb 26. J Cyst Fibros. 2023. PMID: 36849331 Free article.

10

Impact of age at ivacaftor initiation on pulmonary outcomes among people with cystic fibrosis.

Merlo CA, McGarry LJ, Thorat T, Nguyen C, DerSarkissian M, Muthukumar A, Healy J, Brookhart MA, Rubin JL. Merlo CA, et al. Among authors: rubin jl. Thorax. 2024 Sep 18;79(10):915-924. doi: 10.1136/thorax-2023-220559. Thorax. 2024. PMID: 38719441 Free PMC article.

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