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Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin.
Kegelman TP, Wu B, Das SK, Talukdar S, Beckta JM, Hu B, Emdad L, Valerie K, Sarkar D, Furnari FB, Cavenee WK, Wei J, Purves A, De SK, Pellecchia M, Fisher PB. Kegelman TP, et al. Among authors: pellecchia m. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):370-375. doi: 10.1073/pnas.1616100114. Epub 2016 Dec 23. Proc Natl Acad Sci U S A. 2017. PMID: 28011764 Free PMC article.
Efficient synthetic inhibitors of anthrax lethal factor.
Forino M, Johnson S, Wong TY, Rozanov DV, Savinov AY, Li W, Fattorusso R, Becattini B, Orry AJ, Jung D, Abagyan RA, Smith JW, Alibek K, Liddington RC, Strongin AY, Pellecchia M. Forino M, et al. Among authors: pellecchia m. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9499-504. doi: 10.1073/pnas.0502733102. Epub 2005 Jun 27. Proc Natl Acad Sci U S A. 2005. PMID: 15983377 Free PMC article.
Identification of a new JNK inhibitor targeting the JNK-JIP interaction site.
Stebbins JL, De SK, Machleidt T, Becattini B, Vazquez J, Kuntzen C, Chen LH, Cellitti JF, Riel-Mehan M, Emdadi A, Solinas G, Karin M, Pellecchia M. Stebbins JL, et al. Among authors: pellecchia m. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16809-13. doi: 10.1073/pnas.0805677105. Epub 2008 Oct 15. Proc Natl Acad Sci U S A. 2008. PMID: 18922779 Free PMC article.
BI-69A11-mediated inhibition of AKT leads to effective regression of xenograft melanoma.
Gaitonde S, De SK, Tcherpakov M, Dewing A, Yuan H, Riel-Mehan M, Krajewski S, Robertson G, Pellecchia M, Ronai Z. Gaitonde S, et al. Among authors: pellecchia m. Pigment Cell Melanoma Res. 2009 Apr;22(2):187-95. doi: 10.1111/j.1755-148X.2009.00544.x. Epub 2009 Jan 17. Pigment Cell Melanoma Res. 2009. PMID: 19175524 Free PMC article.
Design, synthesis, and structure-activity relationship of substrate competitive, selective, and in vivo active triazole and thiadiazole inhibitors of the c-Jun N-terminal kinase.
De SK, Stebbins JL, Chen LH, Riel-Mehan M, Machleidt T, Dahl R, Yuan H, Emdadi A, Barile E, Chen V, Murphy R, Pellecchia M. De SK, et al. Among authors: pellecchia m. J Med Chem. 2009 Apr 9;52(7):1943-52. doi: 10.1021/jm801503n. J Med Chem. 2009. PMID: 19271755 Free PMC article.
Discovery and binding studies on a series of novel Pin1 ligands.
Wu B, Rega MF, Wei J, Yuan H, Dahl R, Zhang Z, Pellecchia M. Wu B, et al. Among authors: pellecchia m. Chem Biol Drug Des. 2009 Apr;73(4):369-79. doi: 10.1111/j.1747-0285.2009.00795.x. Chem Biol Drug Des. 2009. PMID: 19291099 Free PMC article.
468 results