Shadel GS - Search Results

1

The complete nucleotide sequence of the lux regulon of Vibrio fischeri and the luxABN region of Photobacterium leiognathi and the mechanism of control of bacterial bioluminescence.

Baldwin TO, Devine JH, Heckel RC, Lin JW, Shadel GS. Baldwin TO, et al. Among authors: shadel gs. J Biolumin Chemilumin. 1989 Jul;4(1):326-41. doi: 10.1002/bio.1170040145. J Biolumin Chemilumin. 1989. PMID: 2801220

2

Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling.

Xian H, Watari K, Sanchez-Lopez E, Offenberger J, Onyuru J, Sampath H, Ying W, Hoffman HM, Shadel GS, Karin M. Xian H, et al. Among authors: shadel gs. Immunity. 2022 Aug 9;55(8):1370-1385.e8. doi: 10.1016/j.immuni.2022.06.007. Epub 2022 Jul 13. Immunity. 2022. PMID: 35835107 Free PMC article.

3

Monocyte activation by necrotic cells is promoted by mitochondrial proteins and formyl peptide receptors.

Crouser ED, Shao G, Julian MW, Macre JE, Shadel GS, Tridandapani S, Huang Q, Wewers MD. Crouser ED, et al. Among authors: shadel gs. Crit Care Med. 2009 Jun;37(6):2000-9. doi: 10.1097/CCM.0b013e3181a001ae. Crit Care Med. 2009. PMID: 19384205 Free PMC article.

4

SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2.

Lei Y, Zhang J, Schiavon CR, He M, Chen L, Shen H, Zhang Y, Yin Q, Cho Y, Andrade L, Shadel GS, Hepokoski M, Lei T, Wang H, Zhang J, Yuan JX, Malhotra A, Manor U, Wang S, Yuan ZY, Shyy JY. Lei Y, et al. Among authors: shadel gs. bioRxiv [Preprint]. 2020 Dec 4:2020.12.04.409144. doi: 10.1101/2020.12.04.409144. bioRxiv. 2020. Update in: Circ Res. 2021 Apr 30;128(9):1323-1326. doi: 10.1161/CIRCRESAHA.121.318902 PMID: 33300001 Free PMC article. Updated. Preprint.

5

Into the wild frontier of mitochondrial disease and aging.

Shadel GS. Shadel GS. Methods. 2008 Dec;46(4):239-40. doi: 10.1016/j.ymeth.2008.10.027. Methods. 2008. PMID: 19027636 No abstract available.

6

DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages.

Cobo I, Tanaka TN, Chandra Mangalhara K, Lana A, Yeang C, Han C, Schlachetzki J, Challcombe J, Fixsen BR, Sakai M, Li RZ, Fields H, Mokry M, Tsai RG, Bejar R, Prange K, de Winther M, Shadel GS, Glass CK. Cobo I, et al. Among authors: shadel gs. Immunity. 2022 Aug 9;55(8):1386-1401.e10. doi: 10.1016/j.immuni.2022.06.022. Epub 2022 Aug 4. Immunity. 2022. PMID: 35931086 Free PMC article.

7

Positive autoregulation of the Vibrio fischeri luxR gene. LuxR and autoinducer activate cAMP-catabolite gene activator protein complex-independent and -dependent luxR transcription.

Shadel GS, Baldwin TO. Shadel GS, et al. J Biol Chem. 1992 Apr 15;267(11):7696-702. J Biol Chem. 1992. PMID: 1373136 Free article.

8

Identification of a distantly located regulatory element in the luxD gene required for negative autoregulation of the Vibrio fischeri luxR gene.

Shadel GS, Baldwin TO. Shadel GS, et al. J Biol Chem. 1992 Apr 15;267(11):7690-5. J Biol Chem. 1992. PMID: 1560004 Free article.

9

The Vibrio fischeri LuxR protein is capable of bidirectional stimulation of transcription and both positive and negative regulation of the luxR gene.

Shadel GS, Baldwin TO. Shadel GS, et al. J Bacteriol. 1991 Jan;173(2):568-74. doi: 10.1128/jb.173.2.568-574.1991. J Bacteriol. 1991. PMID: 1987152 Free PMC article.

10

Use of regulated cell lysis in a lethal genetic selection in Escherichia coli: identification of the autoinducer-binding region of the LuxR protein from Vibrio fischeri ATCC 7744.

Shadel GS, Young R, Baldwin TO. Shadel GS, et al. J Bacteriol. 1990 Jul;172(7):3980-7. doi: 10.1128/jb.172.7.3980-3987.1990. J Bacteriol. 1990. PMID: 2141835 Free PMC article.

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