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Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB).
De Rosa M, Lu L, Zamaratski E, Szałaj N, Cao S, Wadensten H, Lenhammar L, Gising J, Roos AK, Huseby DL, Larsson R, Andrén PE, Hughes D, Brandt P, Mowbray SL, Karlén A. De Rosa M, et al. Among authors: mowbray sl. Bioorg Med Chem. 2017 Feb 1;25(3):897-911. doi: 10.1016/j.bmc.2016.12.003. Epub 2016 Dec 7. Bioorg Med Chem. 2017. PMID: 28038943 Free article.
Microwave-enhanced alpha-arylation of a protected glycine in water: evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase.
Lagerlund O, Odell LR, Mowbray SL, Nilsson MT, Krajewski WW, Nordqvist A, Karlén A, Larhed M. Lagerlund O, et al. Among authors: mowbray sl. Comb Chem High Throughput Screen. 2007 Nov;10(9):783-9. doi: 10.2174/138620707783018478. Comb Chem High Throughput Screen. 2007. PMID: 18478959
Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors.
Nilsson MT, Krajewski WW, Yellagunda S, Prabhumurthy S, Chamarahally GN, Siddamadappa C, Srinivasa BR, Yahiaoui S, Larhed M, Karlén A, Jones TA, Mowbray SL. Nilsson MT, et al. Among authors: mowbray sl. J Mol Biol. 2009 Oct 23;393(2):504-13. doi: 10.1016/j.jmb.2009.08.028. Epub 2009 Aug 18. J Mol Biol. 2009. PMID: 19695264 Free article.
Design, synthesis, and X-ray crystallographic studies of α-aryl substituted fosmidomycin analogues as inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
Andaloussi M, Henriksson LM, Więckowska A, Lindh M, Björkelid C, Larsson AM, Suresh S, Iyer H, Srinivasa BR, Bergfors T, Unge T, Mowbray SL, Larhed M, Jones TA, Karlén A. Andaloussi M, et al. Among authors: mowbray sl. J Med Chem. 2011 Jul 28;54(14):4964-76. doi: 10.1021/jm2000085. Epub 2011 Jul 1. J Med Chem. 2011. PMID: 21678907
Synthesis of functionalized cinnamaldehyde derivatives by an oxidative Heck reaction and their use as starting materials for preparation of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.
Nordqvist A, Björkelid C, Andaloussi M, Jansson AM, Mowbray SL, Karlén A, Larhed M. Nordqvist A, et al. Among authors: mowbray sl. J Org Chem. 2011 Nov 4;76(21):8986-98. doi: 10.1021/jo201715x. Epub 2011 Oct 7. J Org Chem. 2011. PMID: 21936546 Free PMC article.
122 results