Bardelli A - Search Results

1

Lemur tyrosine kinase 2 (LMTK2) is a determinant of cell sensitivity to apoptosis by regulating the levels of the BCL2 family members.

Conti A, Majorini MT, Fontanella E, Bardelli A, Giacca M, Delia D, Mano M, Lecis D. Conti A, et al. Among authors: bardelli a. Cancer Lett. 2017 Mar 28;389:59-69. doi: 10.1016/j.canlet.2016.12.025. Epub 2016 Dec 29. Cancer Lett. 2017. PMID: 28040547

2

Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas.

Migliardi G, Sassi F, Torti D, Galimi F, Zanella ER, Buscarino M, Ribero D, Muratore A, Massucco P, Pisacane A, Risio M, Capussotti L, Marsoni S, Di Nicolantonio F, Bardelli A, Comoglio PM, Trusolino L, Bertotti A. Migliardi G, et al. Among authors: bardelli a. Clin Cancer Res. 2012 May 1;18(9):2515-25. doi: 10.1158/1078-0432.CCR-11-2683. Epub 2012 Mar 5. Clin Cancer Res. 2012. PMID: 22392911 Free article.

3

Mixed lineage kinase MLK4 is activated in colorectal cancers where it synergistically cooperates with activated RAS signaling in driving tumorigenesis.

Martini M, Russo M, Lamba S, Vitiello E, Crowley EH, Sassi F, Romanelli D, Frattini M, Marchetti A, Bardelli A. Martini M, et al. Among authors: bardelli a. Cancer Res. 2013 Mar 15;73(6):1912-21. doi: 10.1158/0008-5472.CAN-12-3074. Epub 2013 Jan 14. Cancer Res. 2013. PMID: 23319808 Free article.

4

BRAF V600E is a determinant of sensitivity to proteasome inhibitors.

Zecchin D, Boscaro V, Medico E, Barault L, Martini M, Arena S, Cancelliere C, Bartolini A, Crowley EH, Bardelli A, Gallicchio M, Di Nicolantonio F. Zecchin D, et al. Among authors: bardelli a. Mol Cancer Ther. 2013 Dec;12(12):2950-61. doi: 10.1158/1535-7163.MCT-13-0243. Epub 2013 Oct 9. Mol Cancer Ther. 2013. PMID: 24107445 Free article.

5

Oncogenic KRAS sensitizes premalignant, but not malignant cells, to Noxa-dependent apoptosis through the activation of the MEK/ERK pathway.

Conti A, Majorini MT, Elliott R, Ashworth A, Lord CJ, Cancelliere C, Bardelli A, Seneci P, Walczak H, Delia D, Lecis D. Conti A, et al. Among authors: bardelli a. Oncotarget. 2015 May 10;6(13):10994-1008. doi: 10.18632/oncotarget.3552. Oncotarget. 2015. PMID: 26028667 Free PMC article.

6

Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.

Picco G, Petti C, Sassi F, Grillone K, Migliardi G, Rossi T, Isella C, Di Nicolantonio F, Sarotto I, Sapino A, Bardelli A, Trusolino L, Bertotti A, Medico E. Picco G, et al. Among authors: bardelli a. J Natl Cancer Inst. 2016 Oct 22;109(2):djw209. doi: 10.1093/jnci/djw209. Print 2017 Feb. J Natl Cancer Inst. 2016. PMID: 27771609 Free article.

7

T Cells Expressing Receptor Recombination/Revision Machinery Are Detected in the Tumor Microenvironment and Expanded in Genomically Over-unstable Models.

Morello G, Cancila V, La Rosa M, Germano G, Lecis D, Amodio V, Zanardi F, Iannelli F, Greco D, La Paglia L, Fiannaca A, Urso AM, Graziano G, Ferrari F, Pupa SM, Sangaletti S, Chiodoni C, Pruneri G, Bardelli A, Colombo MP, Tripodo C. Morello G, et al. Among authors: bardelli a. Cancer Immunol Res. 2021 Jul;9(7):825-837. doi: 10.1158/2326-6066.CIR-20-0645. Epub 2021 May 3. Cancer Immunol Res. 2021. PMID: 33941587

8

Hepatocyte growth factor and its receptor, the tyrosine kinase encoded by the c-MET proto-oncogene.

Vigna E, Naldini L, Tamagnone L, Longati P, Bardelli A, Maina F, Ponzetto C, Comoglio PM. Vigna E, et al. Among authors: bardelli a. Cell Mol Biol (Noisy-le-grand). 1994 Jul;40(5):597-604. Cell Mol Biol (Noisy-le-grand). 1994. PMID: 7981617 Review.

9

HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death.

Bardelli A, Longati P, Albero D, Goruppi S, Schneider C, Ponzetto C, Comoglio PM. Bardelli A, et al. EMBO J. 1996 Nov 15;15(22):6205-12. EMBO J. 1996. PMID: 8947043 Free PMC article.

10

Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family.

Olivero M, Valente G, Bardelli A, Longati P, Ferrero N, Cracco C, Terrone C, Rocca-Rossetti S, Comoglio PM, Di Renzo MF. Olivero M, et al. Among authors: bardelli a. Int J Cancer. 1999 Aug 27;82(5):640-3. doi: 10.1002/(sici)1097-0215(19990827)82:5<640::aid-ijc4>3.0.co;2-6. Int J Cancer. 1999. PMID: 10417759

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