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Efficacy of a 12-Week Simeprevir Plus Peginterferon/Ribavirin (PR) Regimen in Treatment-Naïve Patients with Hepatitis C Virus (HCV) Genotype 4 (GT4) Infection and Mild-To-Moderate Fibrosis Displaying Early On-Treatment Virologic Response.
Asselah T, Moreno C, Sarrazin C, Gschwantler M, Foster GR, Craxí A, Buggisch P, Sanai F, Bicer C, Lenz O, Van Dooren G, Nalpas C, Lonjon-Domanec I, Schlag M, Buti M. Asselah T, et al. Among authors: van dooren g. PLoS One. 2017 Jan 5;12(1):e0168713. doi: 10.1371/journal.pone.0168713. eCollection 2017. PLoS One. 2017. PMID: 28056030 Free PMC article. Clinical Trial.
An Open-Label Trial of 12-Week Simeprevir plus Peginterferon/Ribavirin (PR) in Treatment-Naïve Patients with Hepatitis C Virus (HCV) Genotype 1 (GT1).
Asselah T, Moreno C, Sarrazin C, Gschwantler M, Foster GR, Craxí A, Buggisch P, Ryan R, Lenz O, Scott J, Van Dooren G, Lonjon-Domanec I, Schlag M, Buti M. Asselah T, et al. Among authors: van dooren g. PLoS One. 2016 Jul 18;11(7):e0158526. doi: 10.1371/journal.pone.0158526. eCollection 2016. PLoS One. 2016. PMID: 27428331 Free PMC article. Clinical Trial.
Simeprevir plus sofosbuvir for eight or 12 weeks in treatment-naïve and treatment-experienced hepatitis C virus genotype 4 patients with or without cirrhosis.
El Raziky M, Gamil M, Ashour MK, Sameea EA, Doss W, Hamada Y, Van Dooren G, DeMasi R, Keim S, Lonjon-Domanec I, Hammad R, Hashim MS, Hassany M, Waked I. El Raziky M, et al. Among authors: van dooren g. J Viral Hepat. 2017 Feb;24(2):102-110. doi: 10.1111/jvh.12625. Epub 2016 Oct 27. J Viral Hepat. 2017. PMID: 27790789 Clinical Trial.
Real-world evidence from a European cohort study of patients with treatment resistant depression: Baseline patient characteristics.
Heerlein K, Young AH, Otte C, Frodl T, Degraeve G, Hagedoorn W, Oliveira-Maia AJ, Perez Sola V, Rathod S, Rosso G, Sierra P, Morrens J, Van Dooren G, Gali Y, Perugi G. Heerlein K, et al. Among authors: van dooren g. J Affect Disord. 2021 Mar 15;283:115-122. doi: 10.1016/j.jad.2020.11.124. Epub 2020 Nov 30. J Affect Disord. 2021. PMID: 33545659 Free article.
Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b.
Awalt JK, Su W, Nguyen W, Loi K, Jarman KE, Penington JS, Ramesh S, Fairhurst KJ, Yeo T, Park H, Uhlemann AC, Chandra Maity B, De N, Mukherjee P, Chakraborty A, Churchyard A, Famodimu MT, Delves MJ, Baum J, Mittal N, Winzeler EA, Papenfuss AT, Chowdury M, de Koning-Ward TF, Maier AG, van Dooren GG, Baud D, Brand S, Fidock DA, Jackson PF, Cowman AF, Dans MG, Sleebs BE. Awalt JK, et al. Among authors: van dooren gg. Eur J Med Chem. 2024 Dec 15;280:116921. doi: 10.1016/j.ejmech.2024.116921. Epub 2024 Oct 3. Eur J Med Chem. 2024. PMID: 39388903 Free PMC article.
Harnessing cholesterol uptake of malaria parasites for therapeutic applications.
Fraser M, Curtis B, Phillips P, Yates PA, Lam KS, Netzel O, van Dooren GG, Ingmundson A, Matuschewski K, McLeod MD, Maier AG. Fraser M, et al. Among authors: van dooren gg. EMBO Mol Med. 2024 Jul;16(7):1515-1532. doi: 10.1038/s44321-024-00087-1. Epub 2024 Jun 11. EMBO Mol Med. 2024. PMID: 38862600 Free PMC article.
A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites.
Hayward JA, Makota FV, Cihalova D, Leonard RA, Rajendran E, Zwahlen SM, Shuttleworth L, Wiedemann U, Spry C, Saliba KJ, Maier AG, van Dooren GG. Hayward JA, et al. Among authors: van dooren gg. PLoS Pathog. 2023 Jul 20;19(7):e1011517. doi: 10.1371/journal.ppat.1011517. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37471441 Free PMC article.
68 results