Ruterbories K - Search Results

1

Evaluation and Optimization of Blood Micro-Sampling Methods: Serial Sampling in a Cross-Over Design from an Individual Mouse.

Patel NJ, Wickremsinhe E, Hui YH, Barr A, Masterson N, Ruterbories K, Weller J, Hanes J, Kern T, Perkins E. Patel NJ, et al. Among authors: ruterbories k. J Pharm Pharm Sci. 2016 Oct-Dec;19(4):496-510. doi: 10.18433/J3NK60. J Pharm Pharm Sci. 2016. PMID: 28057168 Free article.

2

Dried blood spot sampling: coupling bioanalytical feasibility, blood-plasma partitioning and transferability to in vivo preclinical studies.

Wickremsinhe ER, Abdul BG, Huang NH, Richard JW, Hanes JL, Ruterbories KJ, Perkins EJ, Chaudhary AK. Wickremsinhe ER, et al. Among authors: ruterbories kj. Bioanalysis. 2011 Jul;3(14):1635-46. doi: 10.4155/bio.11.124. Bioanalysis. 2011. PMID: 21756096

3

Preclinical bridging studies: understanding dried blood spot and plasma exposure profiles.

Wickremsinhe ER, Huang NH, Abdul BG, Knotts K, Ruterbories KJ, Manro JR. Wickremsinhe ER, et al. Among authors: ruterbories kj. Bioanalysis. 2013 Jan;5(2):159-70. doi: 10.4155/bio.12.309. Bioanalysis. 2013. PMID: 23330559

4

Validation of 96-well equilibrium dialysis with non-radiolabeled drug for definitive measurement of protein binding and application to clinical development of highly-bound drugs.

Zamek-Gliszczynski MJ, Ruterbories KJ, Ajamie RT, Wickremsinhe ER, Pothuri L, Rao MV, Basavanakatti VN, Pinjari J, Ramanathan VK, Chaudhary AK. Zamek-Gliszczynski MJ, et al. Among authors: ruterbories kj. J Pharm Sci. 2011 Jun;100(6):2498-507. doi: 10.1002/jps.22452. Epub 2011 Jan 6. J Pharm Sci. 2011. PMID: 21213309

5

High sensitive assay employing column switching chromatography to enable simultaneous quantification of an amide prodrug of gemcitabine (LY2334737), gemcitabine, and its metabolite dFdU in human plasma by LC-MS/MS.

Wickremsinhe ER, Lee LB, Schmalz CA, Torchia J, Ruterbories KJ. Wickremsinhe ER, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Aug 1;932:117-22. doi: 10.1016/j.jchromb.2013.06.008. Epub 2013 Jun 13. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 23831704

6

A Semi-Physiologically Based Pharmacokinetic Model Describing the Altered Metabolism of Midazolam Due to Inflammation in Mice.

Varkhede N, Patel N, Chang W, Ruterbories K, Forrest ML. Varkhede N, et al. Among authors: ruterbories k. Pharm Res. 2018 Jun 21;35(8):162. doi: 10.1007/s11095-018-2447-9. Pharm Res. 2018. PMID: 29931580 Free PMC article.

7

Correction to: A Semi-Physiologically Based Pharmacokinetic Model Describing the Altered Metabolism of Midazolam Due to Inflammation in Mice.

Varkhede N, Patel N, Chang W, Ruterbories K, Forrest ML. Varkhede N, et al. Among authors: ruterbories k. Pharm Res. 2018 Jul 25;35(9):180. doi: 10.1007/s11095-018-2463-9. Pharm Res. 2018. PMID: 30046910

8

Stereoselective metabolism of prasugrel in humans using a novel chiral liquid chromatography-tandem mass spectrometry method.

Wickremsinhe ER, Tian Y, Ruterbories KJ, Verburg EM, Weerakkody GJ, Kurihara A, Farid NA. Wickremsinhe ER, et al. Drug Metab Dispos. 2007 Jun;35(6):917-21. doi: 10.1124/dmd.106.014530. Epub 2007 Mar 12. Drug Metab Dispos. 2007. PMID: 17353347 Clinical Trial.

9

The biotransformation of prasugrel, a new thienopyridine prodrug, by the human carboxylesterases 1 and 2.

Williams ET, Jones KO, Ponsler GD, Lowery SM, Perkins EJ, Wrighton SA, Ruterbories KJ, Kazui M, Farid NA. Williams ET, et al. Drug Metab Dispos. 2008 Jul;36(7):1227-32. doi: 10.1124/dmd.107.020248. Epub 2008 Mar 27. Drug Metab Dispos. 2008. PMID: 18372401

10

Characterization of the expression and activity of carboxylesterases 1 and 2 from the beagle dog, cynomolgus monkey, and human.

Williams ET, Bacon JA, Bender DM, Lowinger JJ, Guo WK, Ehsani ME, Wang X, Wang H, Qian YW, Ruterbories KJ, Wrighton SA, Perkins EJ. Williams ET, et al. Drug Metab Dispos. 2011 Dec;39(12):2305-13. doi: 10.1124/dmd.111.041335. Epub 2011 Sep 14. Drug Metab Dispos. 2011. PMID: 21918037

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