Chien WW - Search Results

1

Hearing Loss after Round Window Surgery in Mice Is due to Middle Ear Effusion.

Zhu BZ, Saleh J, Isgrig KT, Cunningham LL, Chien WW. Zhu BZ, et al. Among authors: chien ww. Audiol Neurootol. 2016;21(6):356-364. doi: 10.1159/000449239. Epub 2017 Jan 10. Audiol Neurootol. 2016. PMID: 28068659 Free PMC article.

2

Gene therapy for sensorineural hearing loss.

Chien WW, Monzack EL, McDougald DS, Cunningham LL. Chien WW, et al. Ear Hear. 2015 Jan;36(1):1-7. doi: 10.1097/AUD.0000000000000088. Ear Hear. 2015. PMID: 25166629 Review.

3

Cochlear gene transfer mediated by adeno-associated virus: Comparison of two surgical approaches.

Chien WW, McDougald DS, Roy S, Fitzgerald TS, Cunningham LL. Chien WW, et al. Laryngoscope. 2015 Nov;125(11):2557-64. doi: 10.1002/lary.25317. Epub 2015 Apr 17. Laryngoscope. 2015. PMID: 25891801

4

Gene Therapy Restores Hair Cell Stereocilia Morphology in Inner Ears of Deaf Whirler Mice.

Chien WW, Isgrig K, Roy S, Belyantseva IA, Drummond MC, May LA, Fitzgerald TS, Friedman TB, Cunningham LL. Chien WW, et al. Mol Ther. 2016 Feb;24(1):17-25. doi: 10.1038/mt.2015.150. Epub 2015 Aug 26. Mol Ther. 2016. PMID: 26307667 Free PMC article.

5

Gene Therapy Restores Balance and Auditory Functions in a Mouse Model of Usher Syndrome.

Isgrig K, Shteamer JW, Belyantseva IA, Drummond MC, Fitzgerald TS, Vijayakumar S, Jones SM, Griffith AJ, Friedman TB, Cunningham LL, Chien WW. Isgrig K, et al. Among authors: chien ww. Mol Ther. 2017 Mar 1;25(3):780-791. doi: 10.1016/j.ymthe.2017.01.007. Epub 2017 Feb 21. Mol Ther. 2017. PMID: 28254438 Free PMC article.

6

Posterior Semicircular Canal Approach for Inner Ear Gene Delivery in Neonatal Mouse.

Isgrig K, Chien WW. Isgrig K, et al. Among authors: chien ww. J Vis Exp. 2018 Mar 2;(133):56648. doi: 10.3791/56648. J Vis Exp. 2018. PMID: 29553564 Free PMC article.

7

A CEP290 C-Terminal Domain Complements the Mutant CEP290 of Rd16 Mice In Trans and Rescues Retinal Degeneration.

Mookherjee S, Chen HY, Isgrig K, Yu W, Hiriyanna S, Levron R, Li T, Colosi P, Chien W, Swaroop A, Wu Z. Mookherjee S, et al. Cell Rep. 2018 Oct 16;25(3):611-623.e6. doi: 10.1016/j.celrep.2018.09.043. Cell Rep. 2018. PMID: 30332642 Free PMC article.

8

AAV2.7m8 is a powerful viral vector for inner ear gene therapy.

Isgrig K, McDougald DS, Zhu J, Wang HJ, Bennett J, Chien WW. Isgrig K, et al. Among authors: chien ww. Nat Commun. 2019 Jan 25;10(1):427. doi: 10.1038/s41467-018-08243-1. Nat Commun. 2019. PMID: 30683875 Free PMC article.

9

Surgical Methods for Inner Ear Gene Delivery in Neonatal Mouse.

Isgrig K, Chien WW. Isgrig K, et al. Among authors: chien ww. Methods Mol Biol. 2019;1937:221-226. doi: 10.1007/978-1-4939-9065-8_13. Methods Mol Biol. 2019. PMID: 30706399 Free PMC article.

10

Refining surgical techniques for efficient posterior semicircular canal gene delivery in the adult mammalian inner ear with minimal hearing loss.

Zhu J, Choi JW, Ishibashi Y, Isgrig K, Grati M, Bennett J, Chien W. Zhu J, et al. Sci Rep. 2021 Sep 22;11(1):18856. doi: 10.1038/s41598-021-98412-y. Sci Rep. 2021. PMID: 34552193 Free PMC article.

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