Hartman JH - Search Results

1

1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice.

Hartman JH, Miller GP, Caro AA, Byrum SD, Orr LM, Mackintosh SG, Tackett AJ, MacMillan-Crow LA, Hallberg LM, Ameredes BT, Boysen G. Hartman JH, et al. Toxicology. 2017 Mar 1;378:114-124. doi: 10.1016/j.tox.2017.01.005. Epub 2017 Jan 9. Toxicology. 2017. PMID: 28082109 Free PMC article.

2

Cooperative effects for CYP2E1 differ between styrene and its metabolites.

Hartman JH, Boysen G, Miller GP. Hartman JH, et al. Xenobiotica. 2013 Sep;43(9):755-64. doi: 10.3109/00498254.2012.760764. Epub 2013 Jan 18. Xenobiotica. 2013. PMID: 23327532 Free PMC article.

3

Differences in butadiene adduct formation between rats and mice not due to selective inhibition of CYP2E1 by butadiene metabolites.

Pianalto KM, Hartman JH, Boysen G, Miller GP. Pianalto KM, et al. Among authors: hartman jh. Toxicol Lett. 2013 Nov 25;223(2):221-7. doi: 10.1016/j.toxlet.2013.08.025. Epub 2013 Sep 8. Toxicol Lett. 2013. PMID: 24021170 Free PMC article.

4

Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity.

Hartman JH, Miller GP, Boysen G. Hartman JH, et al. Toxicology. 2014 Apr 6;318:51-8. doi: 10.1016/j.tox.2014.02.003. Epub 2014 Feb 18. Toxicology. 2014. PMID: 24561005 Free PMC article.

5

Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates.

Hartman JH, Martin HC, Caro AA, Pearce AR, Miller GP. Hartman JH, et al. Toxicology. 2015 Dec 2;338:47-58. doi: 10.1016/j.tox.2015.10.001. Epub 2015 Oct 14. Toxicology. 2015. PMID: 26463279 Free PMC article.

6

Toxicological Implications of Mitochondrial Localization of CYP2E1.

Hartman JH, Miller GP, Meyer JN. Hartman JH, et al. Toxicol Res (Camb). 2017;6(3):273-289. doi: 10.1039/C7TX00020K. Epub 2017 Mar 14. Toxicol Res (Camb). 2017. PMID: 28989700 Free PMC article.

7

CYP2E1 metabolism of styrene involves allostery.

Hartman JH, Boysen G, Miller GP. Hartman JH, et al. Drug Metab Dispos. 2012 Oct;40(10):1976-83. doi: 10.1124/dmd.112.046698. Epub 2012 Jul 17. Drug Metab Dispos. 2012. PMID: 22807108 Free PMC article.

8

CYP2E1 hydroxylation of aniline involves negative cooperativity.

Hartman JH, Knott K, Miller GP. Hartman JH, et al. Biochem Pharmacol. 2014 Feb 1;87(3):523-33. doi: 10.1016/j.bcp.2013.12.003. Epub 2013 Dec 15. Biochem Pharmacol. 2014. PMID: 24345333

9

Structural basis for cooperative binding of azoles to CYP2E1 as interpreted through guided molecular dynamics simulations.

Levy JW, Hartman JH, Perry MD Jr, Miller GP. Levy JW, et al. Among authors: hartman jh. J Mol Graph Model. 2015 Mar;56:43-52. doi: 10.1016/j.jmgm.2014.11.013. Epub 2014 Dec 6. J Mol Graph Model. 2015. PMID: 25544389 Free PMC article.

10

Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures.

Hartman JH, Letzig LG, Roberts DW, James LP, Fifer EK, Miller GP. Hartman JH, et al. Biochem Pharmacol. 2015 Oct 1;97(3):341-9. doi: 10.1016/j.bcp.2015.07.026. Epub 2015 Jul 28. Biochem Pharmacol. 2015. PMID: 26225832 Free PMC article.

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