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Radiosynthesis and Evaluation of [11C]3-Hydroxycyclopent-1-enecarboxylic Acid as Potential PET Ligand for the High-Affinity γ-Hydroxybutyric Acid Binding Sites.
Jensen CH, Hansen HD, Bay T, Vogensen SB, Lehel S, Thiesen L, Bundgaard C, Clausen RP, Knudsen GM, Herth MM, Wellendorph P, Frølund B. Jensen CH, et al. Among authors: wellendorph p. ACS Chem Neurosci. 2017 Jan 18;8(1):22-27. doi: 10.1021/acschemneuro.6b00335. Epub 2016 Nov 17. ACS Chem Neurosci. 2017. PMID: 28095676
Design, synthesis, and in vitro pharmacology of new radiolabeled gamma-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity gamma-hydroxybutyric acid binding sites.
Sabbatini P, Wellendorph P, Høg S, Pedersen MH, Bräuner-Osborne H, Martiny L, Frølund B, Clausen RP. Sabbatini P, et al. Among authors: wellendorph p. J Med Chem. 2010 Sep 9;53(17):6506-10. doi: 10.1021/jm1006325. J Med Chem. 2010. PMID: 20715819
α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB).
Absalom N, Eghorn LF, Villumsen IS, Karim N, Bay T, Olsen JV, Knudsen GM, Bräuner-Osborne H, Frølund B, Clausen RP, Chebib M, Wellendorph P. Absalom N, et al. Among authors: wellendorph p. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13404-9. doi: 10.1073/pnas.1204376109. Epub 2012 Jul 2. Proc Natl Acad Sci U S A. 2012. PMID: 22753476 Free PMC article.
Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties.
Jensen AA, Plath N, Pedersen MH, Isberg V, Krall J, Wellendorph P, Stensbøl TB, Gloriam DE, Krogsgaard-Larsen P, Frølund B. Jensen AA, et al. Among authors: wellendorph p. J Med Chem. 2013 Feb 14;56(3):1211-27. doi: 10.1021/jm301656h. Epub 2013 Jan 17. J Med Chem. 2013. PMID: 23301527
95 results