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Page 1
The virtual cell based assay: Current status and future perspectives.
Graepel R, Lamon L, Asturiol D, Berggren E, Joossens E, Paini A, Prieto P, Whelan M, Worth A. Graepel R, et al. Among authors: whelan m. Toxicol In Vitro. 2017 Dec;45(Pt 2):258-267. doi: 10.1016/j.tiv.2017.01.009. Epub 2017 Jan 18. Toxicol In Vitro. 2017. PMID: 28108195 Free PMC article.
Assessment of the predictive capacity of the 3T3 Neutral Red Uptake cytotoxicity test method to identify substances not classified for acute oral toxicity (LD50>2000 mg/kg): results of an ECVAM validation study.
Prieto P, Cole T, Curren R, Gibson RM, Liebsch M, Raabe H, Tuomainen AM, Whelan M, Kinsner-Ovaskainen A. Prieto P, et al. Among authors: whelan m. Regul Toxicol Pharmacol. 2013 Apr;65(3):344-65. doi: 10.1016/j.yrtph.2012.11.013. Epub 2012 Dec 13. Regul Toxicol Pharmacol. 2013. PMID: 23246604
Putative adverse outcome pathways relevant to neurotoxicity.
Bal-Price A, Crofton KM, Sachana M, Shafer TJ, Behl M, Forsby A, Hargreaves A, Landesmann B, Lein PJ, Louisse J, Monnet-Tschudi F, Paini A, Rolaki A, Schrattenholz A, Suñol C, van Thriel C, Whelan M, Fritsche E. Bal-Price A, et al. Among authors: whelan m. Crit Rev Toxicol. 2015 Jan;45(1):83-91. doi: 10.3109/10408444.2014.981331. Crit Rev Toxicol. 2015. PMID: 25605028 Free PMC article. Review.
How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology.
Wittwehr C, Aladjov H, Ankley G, Byrne HJ, de Knecht J, Heinzle E, Klambauer G, Landesmann B, Luijten M, MacKay C, Maxwell G, Meek ME, Paini A, Perkins E, Sobanski T, Villeneuve D, Waters KM, Whelan M. Wittwehr C, et al. Among authors: whelan m. Toxicol Sci. 2017 Feb;155(2):326-336. doi: 10.1093/toxsci/kfw207. Epub 2016 Dec 19. Toxicol Sci. 2017. PMID: 27994170 Free PMC article.
Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines.
Hansjosten I, Rapp J, Reiner L, Vatter R, Fritsch-Decker S, Peravali R, Palosaari T, Joossens E, Gerloff K, Macko P, Whelan M, Gilliland D, Ojea-Jimenez I, Monopoli MP, Rocks L, Garry D, Dawson K, Röttgermann PJF, Murschhauser A, Rädler JO, Tang SVY, Gooden P, Belinga-Desaunay MA, Khan AO, Briffa S, Guggenheim E, Papadiamantis A, Lynch I, Valsami-Jones E, Diabaté S, Weiss C. Hansjosten I, et al. Among authors: whelan m. Arch Toxicol. 2018 Feb;92(2):633-649. doi: 10.1007/s00204-017-2106-7. Epub 2017 Nov 8. Arch Toxicol. 2018. PMID: 29119250
531 results