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Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance.
Wada T, Ishikawa A, Watanabe E, Nakamura Y, Aruga Y, Hasegawa H, Onogi Y, Honda H, Nagai Y, Takatsu K, Ishii Y, Sasahara M, Koya D, Tsuneki H, Sasaoka T. Wada T, et al. Among authors: ishii y. J Endocrinol. 2017 Dec;235(3):179-191. doi: 10.1530/JOE-17-0351. Epub 2017 Aug 30. J Endocrinol. 2017. PMID: 28855315
Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet.
Wada T, Miyashita Y, Sasaki M, Aruga Y, Nakamura Y, Ishii Y, Sasahara M, Kanasaki K, Kitada M, Koya D, Shimano H, Tsuneki H, Sasaoka T. Wada T, et al. Among authors: ishii y. Am J Physiol Endocrinol Metab. 2013 Dec 1;305(11):E1415-25. doi: 10.1152/ajpendo.00419.2013. Epub 2013 Oct 15. Am J Physiol Endocrinol Metab. 2013. PMID: 24129399 Free article.
PDGFRα plays a crucial role in connective tissue remodeling.
Horikawa S, Ishii Y, Hamashima T, Yamamoto S, Mori H, Fujimori T, Shen J, Inoue R, Nishizono H, Itoh H, Majima M, Abraham D, Miyawaki T, Sasahara M. Horikawa S, et al. Among authors: ishii y. Sci Rep. 2015 Dec 7;5:17948. doi: 10.1038/srep17948. Sci Rep. 2015. PMID: 26639755 Free PMC article.
3,998 results