Brody JR - Search Results

1

Alterations of type II classical cadherin, cadherin-10 (CDH10), is associated with pancreatic ductal adenocarcinomas.

Jinawath N, Shiao MS, Norris A, Murphy K, Klein AP, Yonescu R, Iacobuzio-Donahue C, Meeker A, Jinawath A, Yeo CJ, Eshleman JR, Hruban RH, Brody JR, Griffin CA, Harada S. Jinawath N, et al. Among authors: brody jr. Genes Chromosomes Cancer. 2017 May;56(5):427-435. doi: 10.1002/gcc.22447. Epub 2017 Mar 7. Genes Chromosomes Cancer. 2017. PMID: 28124395 Free PMC article.

2

Identification of a functional mutation in pp32r1 (ANP32C).

Kochevar GJ, Brody JR, Kadkol SS, Murphy KM, Pasternack GR. Kochevar GJ, et al. Among authors: brody jr. Hum Mutat. 2004 Jun;23(6):546-51. doi: 10.1002/humu.20030. Hum Mutat. 2004. PMID: 15146458

3

Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

van der Heijden MS, Brody JR, Gallmeier E, Cunningham SC, Dezentje DA, Shen D, Hruban RH, Kern SE. van der Heijden MS, et al. Among authors: brody jr. Am J Pathol. 2004 Aug;165(2):651-7. doi: 10.1016/S0002-9440(10)63329-9. Am J Pathol. 2004. PMID: 15277238 Free PMC article.

4

In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor.

van der Heijden MS, Brody JR, Dezentje DA, Gallmeier E, Cunningham SC, Swartz MJ, DeMarzo AM, Offerhaus GJ, Isacoff WH, Hruban RH, Kern SE. van der Heijden MS, et al. Among authors: brody jr. Clin Cancer Res. 2005 Oct 15;11(20):7508-15. doi: 10.1158/1078-0432.CCR-05-1048. Clin Cancer Res. 2005. PMID: 16243825

5

A proposed clinical test for monitoring fluoropyrimidine therapy: detection and stability of thymidylate synthase ternary complexes.

Brody JR, Gallmeier E, Yoshimura K, Hucl T, Kulesza P, Canto MI, Hruban RH, Schulick RD, Kern SE. Brody JR, et al. Cancer Biol Ther. 2006 Aug;5(8):923-7. doi: 10.4161/cbt.5.8.2976. Epub 2006 Aug 2. Cancer Biol Ther. 2006. PMID: 16855390 Free article.

6

Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: a model for patient classification to aid fluoropyrimidine therapy.

Brody JR, Hucl T, Gallmeier E, Winter JM, Kern SE, Murphy KM. Brody JR, et al. Cancer Res. 2006 Oct 1;66(19):9369-73. doi: 10.1158/0008-5472.CAN-06-2165. Cancer Res. 2006. PMID: 17018589

7

Reduction of pp32 expression in poorly differentiated pancreatic ductal adenocarcinomas and intraductal papillary mucinous neoplasms with moderate dysplasia.

Brody JR, Witkiewicz A, Williams TK, Kadkol SS, Cozzitorto J, Durkan B, Pasternack GR, Yeo CJ. Brody JR, et al. Mod Pathol. 2007 Dec;20(12):1238-44. doi: 10.1038/modpathol.3800974. Epub 2007 Sep 28. Mod Pathol. 2007. PMID: 17906614 Free article.

8

High cancer-specific expression of mesothelin (MSLN) is attributable to an upstream enhancer containing a transcription enhancer factor dependent MCAT motif.

Hucl T, Brody JR, Gallmeier E, Iacobuzio-Donahue CA, Farrance IK, Kern SE. Hucl T, et al. Among authors: brody jr. Cancer Res. 2007 Oct 1;67(19):9055-65. doi: 10.1158/0008-5472.CAN-07-0474. Cancer Res. 2007. PMID: 17909009

9

Evaluating the drug-target relationship between thymidylate synthase expression and tumor response to 5-fluorouracil. Is it time to move forward?

Showalter SL, Showalter TN, Witkiewicz A, Havens R, Kennedy EP, Hucl T, Kern SE, Yeo CJ, Brody JR. Showalter SL, et al. Among authors: brody jr. Cancer Biol Ther. 2008 Jul;7(7):986-94. doi: 10.4161/cbt.7.7.6181. Epub 2008 Apr 21. Cancer Biol Ther. 2008. PMID: 18443433 Free PMC article. Review.

10

Expression of indoleamine 2,3-dioxygenase in metastatic pancreatic ductal adenocarcinoma recruits regulatory T cells to avoid immune detection.

Witkiewicz A, Williams TK, Cozzitorto J, Durkan B, Showalter SL, Yeo CJ, Brody JR. Witkiewicz A, et al. Among authors: brody jr. J Am Coll Surg. 2008 May;206(5):849-54; discussion 854-6. doi: 10.1016/j.jamcollsurg.2007.12.014. Epub 2008 Mar 4. J Am Coll Surg. 2008. PMID: 18471709

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