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A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes.
Glasmacher E, Agrawal S, Chang AB, Murphy TL, Zeng W, Vander Lugt B, Khan AA, Ciofani M, Spooner CJ, Rutz S, Hackney J, Nurieva R, Escalante CR, Ouyang W, Littman DR, Murphy KM, Singh H. Glasmacher E, et al. Among authors: vander lugt b. Science. 2012 Nov 16;338(6109):975-80. doi: 10.1126/science.1228309. Epub 2012 Sep 13. Science. 2012. PMID: 22983707 Free PMC article.
Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation.
Williams JW, Tjota MY, Clay BS, Vander Lugt B, Bandukwala HS, Hrusch CL, Decker DC, Blaine KM, Fixsen BR, Singh H, Sciammas R, Sperling AI. Williams JW, et al. Among authors: vander lugt b. Nat Commun. 2013;4:2990. doi: 10.1038/ncomms3990. Nat Commun. 2013. PMID: 24356538 Free PMC article.
Quantitative measurement of the requirement of diverse protein degradation pathways in MHC class I peptide presentation.
Mamrosh JL, Sherman DJ, Cohen JR, Johnston JA, Joubert MK, Li J, Lipford JR, Lomenick B, Moradian A, Prabhu S, Sweredoski MJ, Vander Lugt B, Verma R, Deshaies RJ. Mamrosh JL, et al. Among authors: vander lugt b. Sci Adv. 2023 Jun 23;9(25):eade7890. doi: 10.1126/sciadv.ade7890. Epub 2023 Jun 23. Sci Adv. 2023. PMID: 37352349 Free PMC article.
Blood transcriptomic signature in type-2 biomarker-low severe asthma and asthma control.
Zeng X, Qing J, Li CM, Lu J, Yamawaki T, Hsu YH, Vander Lugt B, Hsu H, Busby J, McDowell PJ, Jackson DJ, Djukanovic R, Matthews JG, Arron JR, Bradding P, Brightling CE, Chaudhuri R, Choy DF, Cowan D, Fowler SJ, Hardman TC, Harrison T, Howarth P, Lordan J, Mansur AH, Menzies-Gow A, Pavord ID, Walker S, Woodcock A, Heaney LG; investigators for the UK MRC Refractory Asthma Stratification Program (RASP-UK). Zeng X, et al. Among authors: vander lugt b. J Allergy Clin Immunol. 2023 Oct;152(4):876-886. doi: 10.1016/j.jaci.2023.05.023. Epub 2023 Jun 12. J Allergy Clin Immunol. 2023. PMID: 37315813 Free article. Clinical Trial.