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Rare Loss-of-Function Variants in NPC1 Predispose to Human Obesity.
Liu R, Zou Y, Hong J, Cao M, Cui B, Zhang H, Chen M, Shi J, Ning T, Zhao S, Liu W, Xiong H, Wei C, Qiu Z, Gu W, Zhang Y, Li W, Miao L, Sun Y, Yang M, Wang R, Ma Q, Xu M, Xu Y, Wang T, Chan KK, Zuo X, Chen H, Qi L, Lai S, Duan S, Song B, Bi Y, Liu S, Wang W, Ning G, Wang J. Liu R, et al. Among authors: chen m, chen h. Diabetes. 2017 Apr;66(4):935-947. doi: 10.2337/db16-0877. Epub 2017 Jan 27. Diabetes. 2017. PMID: 28130309
Ablation of LGR4 promotes energy expenditure by driving white-to-brown fat switch.
Wang J, Liu R, Wang F, Hong J, Li X, Chen M, Ke Y, Zhang X, Ma Q, Wang R, Shi J, Cui B, Gu W, Zhang Y, Zhang Z, Wang W, Xia X, Liu M, Ning G. Wang J, et al. Among authors: chen m. Nat Cell Biol. 2013 Dec;15(12):1455-63. doi: 10.1038/ncb2867. Epub 2013 Nov 10. Nat Cell Biol. 2013. PMID: 24212090
Association of a gain-of-function variant in LGR4 with central obesity.
Zou Y, Ning T, Shi J, Chen M, Ding L, Huang Y, Kauderer S, Xu M, Cui B, Bi Y, Liu S, Hong J, Liu R, Ning G, Wang J. Zou Y, et al. Among authors: chen m. Obesity (Silver Spring). 2017 Jan;25(1):252-260. doi: 10.1002/oby.21704. Epub 2016 Dec 7. Obesity (Silver Spring). 2017. PMID: 27925416 Free article.
IRX3 Promotes the Browning of White Adipocytes and Its Rare Variants are Associated with Human Obesity Risk.
Zou Y, Lu P, Shi J, Liu W, Yang M, Zhao S, Chen N, Chen M, Sun Y, Gao A, Chen Q, Zhang Z, Ma Q, Ning T, Ying X, Jin J, Deng X, Shen B, Zhang Y, Yuan B, Kauderer S, Liu S, Hong J, Liu R, Ning G, Wang W, Gu W, Wang J. Zou Y, et al. Among authors: chen m, chen n, chen q. EBioMedicine. 2017 Oct;24:64-75. doi: 10.1016/j.ebiom.2017.09.010. Epub 2017 Sep 13. EBioMedicine. 2017. PMID: 28988979 Free PMC article.
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