Millson SH - Search Results

1

The crystal structure of the Sgt1-Skp1 complex: the link between Hsp90 and both SCF E3 ubiquitin ligases and kinetochores.

Willhoft O, Kerr R, Patel D, Zhang W, Al-Jassar C, Daviter T, Millson SH, Thalassinos K, Vaughan CK. Willhoft O, et al. Among authors: millson sh. Sci Rep. 2017 Jan 31;7:41626. doi: 10.1038/srep41626. Sci Rep. 2017. PMID: 28139700 Free PMC article.

2

Chaperone ligand-discrimination by the TPR-domain protein Tah1.

Millson SH, Vaughan CK, Zhai C, Ali MM, Panaretou B, Piper PW, Pearl LH, Prodromou C. Millson SH, et al. Biochem J. 2008 Jul 15;413(2):261-8. doi: 10.1042/BJ20080105. Biochem J. 2008. PMID: 18412542 Free PMC article.

3

Hsp90 and phosphorylation of the Slt2(Mpk1) MAP kinase activation loop are essential for catalytic, but not non-catalytic, Slt2-mediated transcription in yeast.

Millson SH, Truman AW, Piper PW. Millson SH, et al. Cell Stress Chaperones. 2022 May;27(3):295-304. doi: 10.1007/s12192-022-01274-0. Epub 2022 Apr 14. Cell Stress Chaperones. 2022. PMID: 35420390 Free PMC article.

4

Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1.

Panaretou B, Siligardi G, Meyer P, Maloney A, Sullivan JK, Singh S, Millson SH, Clarke PA, Naaby-Hansen S, Stein R, Cramer R, Mollapour M, Workman P, Piper PW, Pearl LH, Prodromou C. Panaretou B, et al. Among authors: millson sh. Mol Cell. 2002 Dec;10(6):1307-18. doi: 10.1016/s1097-2765(02)00785-2. Mol Cell. 2002. PMID: 12504007 Free article.

5

Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates sensitivity to the Hsp90 inhibitor radicicol.

Millson SH, Truman AW, Rácz A, Hu B, Panaretou B, Nuttall J, Mollapour M, Söti C, Piper PW. Millson SH, et al. FEBS J. 2007 Sep;274(17):4453-63. doi: 10.1111/j.1742-4658.2007.05974.x. Epub 2007 Aug 6. FEBS J. 2007. PMID: 17681020 Free article.

6

UCS Chaperone Folding of the Myosin Head: A Function That Evolved before Animals and Fungi Diverged from a Common Ancestor More than a Billion Years Ago.

Piper PW, Scott JE, Millson SH. Piper PW, et al. Among authors: millson sh. Biomolecules. 2022 Jul 26;12(8):1028. doi: 10.3390/biom12081028. Biomolecules. 2022. PMID: 35892339 Free PMC article. Review.

7

Structural basis of the radicicol resistance displayed by a fungal hsp90.

Prodromou C, Nuttall JM, Millson SH, Roe SM, Sim TS, Tan D, Workman P, Pearl LH, Piper PW. Prodromou C, et al. Among authors: millson sh. ACS Chem Biol. 2009 Apr 17;4(4):289-97. doi: 10.1021/cb9000316. ACS Chem Biol. 2009. PMID: 19236053

8

Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90.

Millson SH, Chua CS, Roe SM, Polier S, Solovieva S, Pearl LH, Sim TS, Prodromou C, Piper PW. Millson SH, et al. FASEB J. 2011 Nov;25(11):3828-37. doi: 10.1096/fj.11-188821. Epub 2011 Jul 21. FASEB J. 2011. PMID: 21778327

9

UCS protein function is partially restored in the Saccharomyces cerevisiae she4 mutant with expression of the human UNC45-GC, but not UNC45-SM.

Escalante SG, Brightmore JA, Piper PW, Millson SH. Escalante SG, et al. Among authors: millson sh. Cell Stress Chaperones. 2018 Jul;23(4):609-615. doi: 10.1007/s12192-017-0870-1. Epub 2017 Dec 29. Cell Stress Chaperones. 2018. PMID: 29288355 Free PMC article.

10

Mutation of the Ser18 phosphorylation site on the sole Saccharomyces cerevisiae UCS protein, She4, can compromise high-temperature survival.

Gomez-Escalante S, Piper PW, Millson SH. Gomez-Escalante S, et al. Among authors: millson sh. Cell Stress Chaperones. 2017 Jan;22(1):135-141. doi: 10.1007/s12192-016-0750-0. Epub 2016 Nov 25. Cell Stress Chaperones. 2017. PMID: 27888470 Free PMC article.

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