Odermatt A - Search Results

1

Novel 11β-hydroxysteroid dehydrogenase 1 inhibitors reduce cortisol levels in keratinocytes and improve dermal collagen content in human ex vivo skin after exposure to cortisone and UV.

Boudon SM, Vuorinen A, Geotti-Bianchini P, Wandeler E, Kratschmar DV, Heidl M, Campiche R, Jackson E, Odermatt A. Boudon SM, et al. Among authors: odermatt a. PLoS One. 2017 Feb 2;12(2):e0171079. doi: 10.1371/journal.pone.0171079. eCollection 2017. PLoS One. 2017. PMID: 28152550 Free PMC article.

2

Hexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroids.

Nashev LG, Chandsawangbhuwana C, Balazs Z, Atanasov AG, Dick B, Frey FJ, Baker ME, Odermatt A. Nashev LG, et al. Among authors: odermatt a. PLoS One. 2007 Jun 27;2(6):e561. doi: 10.1371/journal.pone.0000561. PLoS One. 2007. PMID: 17593962 Free PMC article.

3

11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose.

Dzyakanchuk AA, Balázs Z, Nashev LG, Amrein KE, Odermatt A. Dzyakanchuk AA, et al. Among authors: odermatt a. Mol Cell Endocrinol. 2009 Mar 25;301(1-2):137-41. doi: 10.1016/j.mce.2008.08.009. Epub 2008 Aug 20. Mol Cell Endocrinol. 2009. PMID: 18778749

4

Dibutyltin disrupts glucocorticoid receptor function and impairs glucocorticoid-induced suppression of cytokine production.

Gumy C, Chandsawangbhuwana C, Dzyakanchuk AA, Kratschmar DV, Baker ME, Odermatt A. Gumy C, et al. Among authors: odermatt a. PLoS One. 2008;3(10):e3545. doi: 10.1371/journal.pone.0003545. Epub 2008 Oct 28. PLoS One. 2008. PMID: 18958157 Free PMC article.

5

Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11beta-hydroxysteroid dehydrogenase 1.

Balázs Z, Nashev LG, Chandsawangbhuwana C, Baker ME, Odermatt A. Balázs Z, et al. Among authors: odermatt a. Mol Cell Endocrinol. 2009 Mar 25;301(1-2):117-22. doi: 10.1016/j.mce.2008.10.021. Epub 2008 Oct 25. Mol Cell Endocrinol. 2009. PMID: 19010388

6

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicines.

Gumy C, Thurnbichler C, Aubry EM, Balazs Z, Pfisterer P, Baumgartner L, Stuppner H, Odermatt A, Rollinger JM. Gumy C, et al. Among authors: odermatt a. Fitoterapia. 2009 Apr;80(3):200-5. doi: 10.1016/j.fitote.2009.01.009. Epub 2009 Jan 24. Fitoterapia. 2009. PMID: 19535018

7

Diazepane-acetamide derivatives as selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.

Odermatt A. Odermatt A. Expert Opin Ther Pat. 2009 Oct;19(10):1477-83. doi: 10.1517/13543770902911490. Expert Opin Ther Pat. 2009. PMID: 19780703

8

The glucocorticoid-activating enzyme 11beta-hydroxysteroid dehydrogenase type 1 has broad substrate specificity: Physiological and toxicological considerations.

Odermatt A, Nashev LG. Odermatt A, et al. J Steroid Biochem Mol Biol. 2010 Mar;119(1-2):1-13. doi: 10.1016/j.jsbmb.2010.01.007. Epub 2010 Jan 25. J Steroid Biochem Mol Biol. 2010. PMID: 20100573 Review.

9

11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches.

Rollinger JM, Kratschmar DV, Schuster D, Pfisterer PH, Gumy C, Aubry EM, Brandstötter S, Stuppner H, Wolber G, Odermatt A. Rollinger JM, et al. Among authors: odermatt a. Bioorg Med Chem. 2010 Feb 15;18(4):1507-15. doi: 10.1016/j.bmc.2010.01.010. Epub 2010 Jan 11. Bioorg Med Chem. 2010. PMID: 20100662

10

Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting 11β-hydroxysteroid dehydrogenase type 2.

Kratschmar DV, Vuorinen A, Da Cunha T, Wolber G, Classen-Houben D, Doblhoff O, Schuster D, Odermatt A. Kratschmar DV, et al. Among authors: odermatt a. J Steroid Biochem Mol Biol. 2011 May;125(1-2):129-42. doi: 10.1016/j.jsbmb.2010.12.019. Epub 2011 Jan 12. J Steroid Biochem Mol Biol. 2011. PMID: 21236343

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