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HADHA, the alpha subunit of the mitochondrial trifunctional protein, is involved in long-chain fatty acid-induced autophagy in intestinal epithelial cells.
Maeyashiki C, Oshima S, Otsubo K, Kobayashi M, Nibe Y, Matsuzawa Y, Onizawa M, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Watanabe M. Maeyashiki C, et al. Among authors: onizawa m. Biochem Biophys Res Commun. 2017 Mar 11;484(3):636-641. doi: 10.1016/j.bbrc.2017.01.159. Epub 2017 Jan 30. Biochem Biophys Res Commun. 2017. PMID: 28153718
Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study.
Peyrin-Biroulet L, Allegretti JR, Rubin DT, Bressler B, Germinaro M, Huang KG, Shipitofsky N, Zhang H, Wilson R, Han C, Feagan BG, Sandborn WJ, Panés J, Hisamatsu T, Lichtenstein GR, Sands BE, Dignass A; QUASAR Study Group. Peyrin-Biroulet L, et al. Gastroenterology. 2023 Dec;165(6):1443-1457. doi: 10.1053/j.gastro.2023.08.038. Epub 2023 Sep 1. Gastroenterology. 2023. PMID: 37659673 Free article. Clinical Trial.
Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis.
Onizawa M, Nagaishi T, Kanai T, Nagano K, Oshima S, Nemoto Y, Yoshioka A, Totsuka T, Okamoto R, Nakamura T, Sakamoto N, Tsuchiya K, Aoki K, Ohya K, Yagita H, Watanabe M. Onizawa M, et al. Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G850-9. doi: 10.1152/ajpgi.00071.2008. Epub 2009 Jan 29. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19179628 Free article.
Myosin light chain kinase expression induced via tumor necrosis factor receptor 2 signaling in the epithelial cells regulates the development of colitis-associated carcinogenesis.
Suzuki M, Nagaishi T, Yamazaki M, Onizawa M, Watabe T, Sakamaki Y, Ichinose S, Totsuka M, Oshima S, Okamoto R, Shimonaka M, Yagita H, Nakamura T, Watanabe M. Suzuki M, et al. Among authors: onizawa m. PLoS One. 2014 Feb 10;9(2):e88369. doi: 10.1371/journal.pone.0088369. eCollection 2014. PLoS One. 2014. PMID: 24520376 Free PMC article.
Receptor-Interacting Protein Kinase 3 (RIPK3) inhibits autophagic flux during necroptosis in intestinal epithelial cells.
Otsubo K, Maeyashiki C, Nibe Y, Tamura A, Aonuma E, Matsuda H, Kobayashi M, Onizawa M, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Torii S, Itakura E, Watanabe M, Oshima S. Otsubo K, et al. Among authors: onizawa m. FEBS Lett. 2020 May;594(10):1586-1595. doi: 10.1002/1873-3468.13748. Epub 2020 Feb 16. FEBS Lett. 2020. PMID: 31997355 Free article.
CEACAM1 specifically suppresses B cell receptor signaling-mediated activation.
Tsugawa N, Yamada D, Watabe T, Onizawa M, Wang S, Nemoto Y, Oshima S, Tsubata T, Adachi T, Kawano Y, Watanabe M, Blumberg RS, Okamoto R, Nagaishi T. Tsugawa N, et al. Among authors: onizawa m. Biochem Biophys Res Commun. 2021 Jan 8;535:99-105. doi: 10.1016/j.bbrc.2020.11.126. Epub 2020 Dec 21. Biochem Biophys Res Commun. 2021. PMID: 33352461 Free PMC article.
42 results