BRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation.
Thirthagiri E, Klarmann KD, Shukla AK, Southon E, Biswas K, Martin BK, North SL, Magidson V, Burkett S, Haines DC, Noer K, Matthai R, Tessarollo L, Loncarek J, Keller JR, Sharan SK.
Thirthagiri E, et al. Among authors: klarmann kd.
Hum Mol Genet. 2016 May 15;25(10):1934-1945. doi: 10.1093/hmg/ddw066. Epub 2016 Feb 26.
Hum Mol Genet. 2016.
PMID: 26920070
Free PMC article.