Fabregat I - Search Results

1

Transforming growth factor-β-induced plasticity causes a migratory stemness phenotype in hepatocellular carcinoma.

Malfettone A, Soukupova J, Bertran E, Crosas-Molist E, Lastra R, Fernando J, Koudelkova P, Rani B, Fabra Á, Serrano T, Ramos E, Mikulits W, Giannelli G, Fabregat I. Malfettone A, et al. Among authors: fabregat i. Cancer Lett. 2017 Apr 28;392:39-50. doi: 10.1016/j.canlet.2017.01.037. Epub 2017 Feb 2. Cancer Lett. 2017. PMID: 28161507

2

Autocrine production of TGF-beta confers resistance to apoptosis after an epithelial-mesenchymal transition process in hepatocytes: Role of EGF receptor ligands.

Del Castillo G, Murillo MM, Alvarez-Barrientos A, Bertran E, Fernández M, Sánchez A, Fabregat I. Del Castillo G, et al. Among authors: fabregat i. Exp Cell Res. 2006 Sep 10;312(15):2860-71. doi: 10.1016/j.yexcr.2006.05.017. Epub 2006 Jun 7. Exp Cell Res. 2006. PMID: 16828470

3

Differential intracellular signalling induced by TGF-beta in rat adult hepatocytes and hepatoma cells: implications in liver carcinogenesis.

Caja L, Ortiz C, Bertran E, Murillo MM, Miró-Obradors MJ, Palacios E, Fabregat I. Caja L, et al. Among authors: fabregat i. Cell Signal. 2007 Apr;19(4):683-94. doi: 10.1016/j.cellsig.2006.09.002. Epub 2006 Sep 16. Cell Signal. 2007. PMID: 17055226

4

TGF-beta dependent regulation of oxygen radicals during transdifferentiation of activated hepatic stellate cells to myofibroblastoid cells.

Proell V, Carmona-Cuenca I, Murillo MM, Huber H, Fabregat I, Mikulits W. Proell V, et al. Among authors: fabregat i. Comp Hepatol. 2007 Feb 20;6:1. doi: 10.1186/1476-5926-6-1. Comp Hepatol. 2007. PMID: 17311678 Free PMC article.

5

Inhibition of the EGF receptor blocks autocrine growth and increases the cytotoxic effects of doxorubicin in rat hepatoma cells: role of reactive oxygen species production and glutathione depletion.

Ortiz C, Caja L, Sancho P, Bertran E, Fabregat I. Ortiz C, et al. Among authors: fabregat i. Biochem Pharmacol. 2008 May 15;75(10):1935-45. doi: 10.1016/j.bcp.2008.02.015. Epub 2008 Feb 19. Biochem Pharmacol. 2008. PMID: 18371937

6

The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms.

Sancho P, Bertran E, Caja L, Carmona-Cuenca I, Murillo MM, Fabregat I. Sancho P, et al. Among authors: fabregat i. Biochim Biophys Acta. 2009 Feb;1793(2):253-63. doi: 10.1016/j.bbamcr.2008.09.003. Epub 2008 Sep 24. Biochim Biophys Acta. 2009. PMID: 18848961 Free article.

7

Role of CXCR4/SDF-1 alpha in the migratory phenotype of hepatoma cells that have undergone epithelial-mesenchymal transition in response to the transforming growth factor-beta.

Bertran E, Caja L, Navarro E, Sancho P, Mainez J, Murillo MM, Vinyals A, Fabra A, Fabregat I. Bertran E, et al. Among authors: fabregat i. Cell Signal. 2009 Nov;21(11):1595-606. doi: 10.1016/j.cellsig.2009.06.006. Epub 2009 Jul 6. Cell Signal. 2009. PMID: 19586611

8

Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-{beta}-induced cell death through impairing up-regulation of the NADPH oxidase NOX4.

Caja L, Sancho P, Bertran E, Iglesias-Serret D, Gil J, Fabregat I. Caja L, et al. Among authors: fabregat i. Cancer Res. 2009 Oct 1;69(19):7595-602. doi: 10.1158/0008-5472.CAN-09-1482. Epub 2009 Sep 22. Cancer Res. 2009. PMID: 19773433

9

NADPH oxidase NOX1 controls autocrine growth of liver tumor cells through up-regulation of the epidermal growth factor receptor pathway.

Sancho P, Fabregat I. Sancho P, et al. Among authors: fabregat i. J Biol Chem. 2010 Aug 6;285(32):24815-24. doi: 10.1074/jbc.M110.114280. Epub 2010 Jun 4. J Biol Chem. 2010. PMID: 20525691 Free PMC article.

10

The transforming growth factor-beta (TGF-β) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells.

Caja L, Bertran E, Campbell J, Fausto N, Fabregat I. Caja L, et al. Among authors: fabregat i. J Cell Physiol. 2011 May;226(5):1214-23. doi: 10.1002/jcp.22439. J Cell Physiol. 2011. PMID: 20945437

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