Ikeda H - Search Results

1

Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo.

Ozaki T, Yamashita K, Goto Y, Shimomura M, Hayashi S, Asamizu S, Sugai Y, Ikeda H, Suga H, Onaka H. Ozaki T, et al. Among authors: ikeda h. Nat Commun. 2017 Feb 6;8:14207. doi: 10.1038/ncomms14207. Nat Commun. 2017. PMID: 28165449 Free PMC article.

2

Genome mining reveals a minimum gene set for the biosynthesis of 32-membered macrocyclic thiopeptides lactazoles.

Hayashi S, Ozaki T, Asamizu S, Ikeda H, Ōmura S, Oku N, Igarashi Y, Tomoda H, Onaka H. Hayashi S, et al. Among authors: ikeda h. Chem Biol. 2014 May 22;21(5):679-88. doi: 10.1016/j.chembiol.2014.03.008. Epub 2014 Apr 24. Chem Biol. 2014. PMID: 24768308

3

pTOYAMAcos, pTYM18, and pTYM19, actinomycete-Escherichia coli integrating vectors for heterologous gene expression.

Onaka H, Taniguchi S, Ikeda H, Igarashi Y, Furumai T. Onaka H, et al. Among authors: ikeda h. J Antibiot (Tokyo). 2003 Nov;56(11):950-6. doi: 10.7164/antibiotics.56.950. J Antibiot (Tokyo). 2003. PMID: 14763561 Free article.

4

In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives.

Kudo K, Hashimoto T, Hashimoto J, Kozone I, Kagaya N, Ueoka R, Nishimura T, Komatsu M, Suenaga H, Ikeda H, Shin-Ya K. Kudo K, et al. Among authors: ikeda h. Nat Commun. 2020 Aug 11;11(1):4022. doi: 10.1038/s41467-020-17769-2. Nat Commun. 2020. PMID: 32782248 Free PMC article.

5

Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution.

Awakawa T, Fujioka T, Zhang L, Hoshino S, Hu Z, Hashimoto J, Kozone I, Ikeda H, Shin-Ya K, Liu W, Abe I. Awakawa T, et al. Among authors: ikeda h. Nat Commun. 2018 Aug 30;9(1):3534. doi: 10.1038/s41467-018-05877-z. Nat Commun. 2018. PMID: 30166552 Free PMC article.

6

Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.

Ikeda H, Ishikawa J, Hanamoto A, Shinose M, Kikuchi H, Shiba T, Sakaki Y, Hattori M, Omura S. Ikeda H, et al. Nat Biotechnol. 2003 May;21(5):526-31. doi: 10.1038/nbt820. Epub 2003 Apr 14. Nat Biotechnol. 2003. PMID: 12692562

7

Novel thioviridamide derivative--JBIR-140: heterologous expression of the gene cluster for thioviridamide biosynthesis.

Izumikawa M, Kozone I, Hashimoto J, Kagaya N, Takagi M, Koiwai H, Komatsu M, Fujie M, Satoh N, Ikeda H, Shin-ya K. Izumikawa M, et al. Among authors: ikeda h. J Antibiot (Tokyo). 2015 Aug;68(8):533-6. doi: 10.1038/ja.2015.20. Epub 2015 Feb 25. J Antibiot (Tokyo). 2015. PMID: 25712397 No abstract available.

8

Neothioviridamide, a Polythioamide Compound Produced by Heterologous Expression of a Streptomyces sp. Cryptic RiPP Biosynthetic Gene Cluster.

Kawahara T, Izumikawa M, Kozone I, Hashimoto J, Kagaya N, Koiwai H, Komatsu M, Fujie M, Sato N, Ikeda H, Shin-Ya K. Kawahara T, et al. Among authors: ikeda h. J Nat Prod. 2018 Feb 23;81(2):264-269. doi: 10.1021/acs.jnatprod.7b00607. Epub 2018 Jan 30. J Nat Prod. 2018. PMID: 29381067

9

Biosynthesis of Quinolidomicin, the Largest Known Macrolide of Terrestrial Origin: Identification and Heterologous Expression of a Biosynthetic Gene Cluster over 200 kb.

Hashimoto T, Hashimoto J, Kozone I, Amagai K, Kawahara T, Takahashi S, Ikeda H, Shin-Ya K. Hashimoto T, et al. Among authors: ikeda h. Org Lett. 2018 Dec 21;20(24):7996-7999. doi: 10.1021/acs.orglett.8b03570. Epub 2018 Dec 13. Org Lett. 2018. PMID: 30543302

10

Mechanism of Action of Prethioviridamide, an Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptide with a Polythioamide Structure.

Takase S, Kurokawa R, Kondoh Y, Honda K, Suzuki T, Kawahara T, Ikeda H, Dohmae N, Osada H, Shin-Ya K, Kushiro T, Yoshida M, Matsumoto K. Takase S, et al. Among authors: ikeda h. ACS Chem Biol. 2019 Aug 16;14(8):1819-1828. doi: 10.1021/acschembio.9b00410. Epub 2019 Jul 31. ACS Chem Biol. 2019. PMID: 31365229

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