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Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Schütte M, Risch T, Abdavi-Azar N, Boehnke K, Schumacher D, Keil M, Yildiriman R, Jandrasits C, Borodina T, Amstislavskiy V, Worth CL, Schweiger C, Liebs S, Lange M, Warnatz HJ, Butcher LM, Barrett JE, Sultan M, Wierling C, Golob-Schwarzl N, Lax S, Uranitsch S, Becker M, Welte Y, Regan JL, Silvestrov M, Kehler I, Fusi A, Kessler T, Herwig R, Landegren U, Wienke D, Nilsson M, Velasco JA, Garin-Chesa P, Reinhard C, Beck S, Schäfer R, Regenbrecht CR, Henderson D, Lange B, Haybaeck J, Keilholz U, Hoffmann J, Lehrach H, Yaspo ML. Schütte M, et al. Among authors: kessler t. Nat Commun. 2017 Feb 10;8:14262. doi: 10.1038/ncomms14262. Nat Commun. 2017. PMID: 28186126 Free PMC article.
Support of a molecular tumour board by an evidence-based decision management system for precision oncology.
Lamping M, Benary M, Leyvraz S, Messerschmidt C, Blanc E, Kessler T, Schütte M, Lenze D, Jöhrens K, Burock S, Klinghammer K, Ochsenreither S, Sers C, Schäfer R, Tinhofer I, Beule D, Klauschen F, Yaspo ML, Keilholz U, Rieke DT. Lamping M, et al. Among authors: kessler t. Eur J Cancer. 2020 Mar;127:41-51. doi: 10.1016/j.ejca.2019.12.017. Epub 2020 Jan 23. Eur J Cancer. 2020. PMID: 31982633
Efficient Parameter Estimation Enables the Prediction of Drug Response Using a Mechanistic Pan-Cancer Pathway Model.
Fröhlich F, Kessler T, Weindl D, Shadrin A, Schmiester L, Hache H, Muradyan A, Schütte M, Lim JH, Heinig M, Theis FJ, Lehrach H, Wierling C, Lange B, Hasenauer J. Fröhlich F, et al. Among authors: kessler t. Cell Syst. 2018 Dec 26;7(6):567-579.e6. doi: 10.1016/j.cels.2018.10.013. Epub 2018 Nov 28. Cell Syst. 2018. PMID: 30503647 Free article.
Biomarker-driven therapies for metastatic uveal melanoma: A prospective precision oncology feasibility study.
Leyvraz S, Konietschke F, Peuker C, Schütte M, Kessler T, Ochsenreither S, Ditzhaus M, Sprünken ED, Dörpholz G, Lamping M, Rieke DT, Klinghammer K, Burock S, Ulrich C, Poch G, Schäfer R, Klauschen F, Joussen A, Yaspo ML, Keilholz U. Leyvraz S, et al. Among authors: kessler t. Eur J Cancer. 2022 Jul;169:146-155. doi: 10.1016/j.ejca.2022.04.004. Epub 2022 May 12. Eur J Cancer. 2022. PMID: 35569281
Proteomic and functional analysis of the mitotic Drosophila centrosome.
Müller H, Schmidt D, Steinbrink S, Mirgorodskaya E, Lehmann V, Habermann K, Dreher F, Gustavsson N, Kessler T, Lehrach H, Herwig R, Gobom J, Ploubidou A, Boutros M, Lange BM. Müller H, et al. Among authors: kessler t. EMBO J. 2010 Oct 6;29(19):3344-57. doi: 10.1038/emboj.2010.210. Epub 2010 Sep 3. EMBO J. 2010. PMID: 20818332 Free PMC article.
Effect of Linearization in a WNT Signaling Model.
Ciușdel CF, Coman S, Boldișor C, Kessler T, Muradyan A, Kovachev A, Lehrach H, Wierling C, Itu LM. Ciușdel CF, et al. Among authors: kessler t. Comput Math Methods Med. 2019 Jun 10;2019:8461820. doi: 10.1155/2019/8461820. eCollection 2019. Comput Math Methods Med. 2019. PMID: 31281412 Free PMC article.
715 results