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Proteasome impairment in neural cells derived from HMSN-P patient iPSCs.
Murakami N, Imamura K, Izumi Y, Egawa N, Tsukita K, Enami T, Yamamoto T, Kawarai T, Kaji R, Inoue H. Murakami N, et al. Among authors: kawarai t. Mol Brain. 2017 Feb 15;10(1):7. doi: 10.1186/s13041-017-0286-y. Mol Brain. 2017. PMID: 28196470 Free PMC article.
[Pathomechanisms of motor neuron death by mutant TFG].
Kawarai T, Morita M, Morigaki R, Fujita K, Nodera H, Izumi Y, Goto S, Nakano I, Kaji R. Kawarai T, et al. Rinsho Shinkeigaku. 2013;23(11):1199. doi: 10.5692/clinicalneurol.53.1199. Rinsho Shinkeigaku. 2013. PMID: 24291928 Japanese.
MiR-33a is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons.
Nakazeki F, Tsuge I, Horie T, Imamura K, Tsukita K, Hotta A, Baba O, Kuwabara Y, Nishino T, Nakao T, Nishiga M, Nishi H, Nakashima Y, Ide Y, Koyama S, Kimura M, Tsuji S, Naitoh M, Suzuki S, Izumi Y, Kawarai T, Kaji R, Kimura T, Inoue H, Ono K. Nakazeki F, et al. Among authors: kawarai t. Clin Sci (Lond). 2019 Feb 22;133(4):583-595. doi: 10.1042/CS20180980. Print 2019 Feb 28. Clin Sci (Lond). 2019. PMID: 30777884
The TRK-fused gene is mutated in hereditary motor and sensory neuropathy with proximal dominant involvement.
Ishiura H, Sako W, Yoshida M, Kawarai T, Tanabe O, Goto J, Takahashi Y, Date H, Mitsui J, Ahsan B, Ichikawa Y, Iwata A, Yoshino H, Izumi Y, Fujita K, Maeda K, Goto S, Koizumi H, Morigaki R, Ikemura M, Yamauchi N, Murayama S, Nicholson GA, Ito H, Sobue G, Nakagawa M, Kaji R, Tsuji S. Ishiura H, et al. Among authors: kawarai t. Am J Hum Genet. 2012 Aug 10;91(2):320-9. doi: 10.1016/j.ajhg.2012.07.014. Am J Hum Genet. 2012. PMID: 22883144 Free PMC article.
[Dystonia genes and elucidation of their roles in dystonia pathogenesis].
Kawarai T, Miyamoto R, Murakami N, Miyazaki Y, Koizumi H, Sako W, Mukai Y, Sato K, Matsumoto S, Sakamoto T, Izumi Y, Kaji R. Kawarai T, et al. Rinsho Shinkeigaku. 2013;53(6):419-29. doi: 10.5692/clinicalneurol.53.419. Rinsho Shinkeigaku. 2013. PMID: 23782819 Review. Japanese.
172 results