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A Novel Small-Molecule Inhibitor of the Mycobacterium tuberculosis Demethylmenaquinone Methyltransferase MenG Is Bactericidal to Both Growing and Nutritionally Deprived Persister Cells.
Sukheja P, Kumar P, Mittal N, Li SG, Singleton E, Russo R, Perryman AL, Shrestha R, Awasthi D, Husain S, Soteropoulos P, Brukh R, Connell N, Freundlich JS, Alland D. Sukheja P, et al. Among authors: shrestha r. mBio. 2017 Feb 14;8(1):e02022-16. doi: 10.1128/mBio.02022-16. mBio. 2017. PMID: 28196957 Free PMC article.
Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
Kumar P, Capodagli GC, Awasthi D, Shrestha R, Maharaja K, Sukheja P, Li SG, Inoyama D, Zimmerman M, Ho Liang HP, Sarathy J, Mina M, Rasic G, Russo R, Perryman AL, Richmann T, Gupta A, Singleton E, Verma S, Husain S, Soteropoulos P, Wang Z, Morris R, Porter G, Agnihotri G, Salgame P, Ekins S, Rhee KY, Connell N, Dartois V, Neiditch MB, Freundlich JS, Alland D. Kumar P, et al. Among authors: shrestha r. mBio. 2018 Dec 18;9(6):e02101-17. doi: 10.1128/mBio.02101-17. mBio. 2018. PMID: 30563908 Free PMC article.
Optimization of N-benzyl-5-nitrofuran-2-carboxamide as an antitubercular agent.
Gallardo-Macias R, Kumar P, Jaskowski M, Richmann T, Shrestha R, Russo R, Singleton E, Zimmerman MD, Ho HP, Dartois V, Connell N, Alland D, Freundlich JS. Gallardo-Macias R, et al. Among authors: shrestha r. Bioorg Med Chem Lett. 2019 Feb 15;29(4):601-606. doi: 10.1016/j.bmcl.2018.12.053. Epub 2018 Dec 24. Bioorg Med Chem Lett. 2019. PMID: 30600207 Free PMC article.
A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.
Inoyama D, Awasthi D, Capodagli GC, Tsotetsi K, Sukheja P, Zimmerman M, Li SG, Jadhav R, Russo R, Wang X, Grady C, Richmann T, Shrestha R, Li L, Ahn YM, Ho Liang HP, Mina M, Park S, Perlin DS, Connell N, Dartois V, Alland D, Neiditch MB, Kumar P, Freundlich JS. Inoyama D, et al. Among authors: shrestha r. Cell Chem Biol. 2020 May 21;27(5):560-570.e10. doi: 10.1016/j.chembiol.2020.02.007. Epub 2020 Mar 19. Cell Chem Biol. 2020. PMID: 32197094 Free PMC article.
A Novel Oral GyrB/ParE Dual Binding Inhibitor Effective against Multidrug-Resistant Neisseria gonorrhoeae and Other High-Threat Pathogens.
Park S, Russo R, Westfall L, Shrestha R, Zimmerman M, Dartois V, Kurepina N, Kreiswirth B, Singleton E, Li SG, Mittal N, Ahn YM, Bilotta J, Connolly KL, Jerse AE, Freundlich JS, Perlin DS. Park S, et al. Among authors: shrestha r. Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0041422. doi: 10.1128/aac.00414-22. Epub 2022 Aug 16. Antimicrob Agents Chemother. 2022. PMID: 35972242 Free PMC article.
Geospatial distribution of Hepatitis E seroprevalence in Nepal, 2021.
Rhee C, Dighe A, Katuwal N, Cho H, Mraidi R, Tamrakar D, Lim JK, Poudyal N, Park IY, Kim DR, Amatya R, Shrestha R, Azman AS, Lynch J. Rhee C, et al. Among authors: shrestha r. PLoS Negl Trop Dis. 2024 Dec 23;18(12):e0012746. doi: 10.1371/journal.pntd.0012746. Online ahead of print. PLoS Negl Trop Dis. 2024. PMID: 39715282 Free article.
Acupuncture for hypoxic ischemic encephalopathy in neonates.
Sibrecht G, Wong MY, Shrestha R, Bruschettini M. Sibrecht G, et al. Among authors: shrestha r. Cochrane Database Syst Rev. 2024 Dec 18;12(12):CD007968. doi: 10.1002/14651858.CD007968.pub3. Cochrane Database Syst Rev. 2024. PMID: 39692246 Review.
1,899 results