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Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age.
Davies L, Jin J, Shen W, Tsui H, Shi Y, Wang Y, Zhang Y, Hao G, Wu J, Chen S, Fraser JA, Dong N, Christoffels V, Ravens U, Huang CL, Zhang H, Cartwright EJ, Wang X, Lei M. Davies L, et al. Among authors: chen s. J Am Heart Assoc. 2014 Apr 10;3(2):e000340. doi: 10.1161/JAHA.113.000340. J Am Heart Assoc. 2014. PMID: 24721794 Free PMC article.
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