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Dysfunctional activation of neurotensin/IL-8 pathway in hepatocellular carcinoma is associated with increased inflammatory response in microenvironment, more epithelial mesenchymal transition in cancer and worse prognosis in patients.
Yu J, Ren X, Chen Y, Liu P, Wei X, Li H, Ying G, Chen K, Winkler H, Hao X. Yu J, et al. Among authors: liu p. PLoS One. 2013;8(2):e56069. doi: 10.1371/journal.pone.0056069. Epub 2013 Feb 13. PLoS One. 2013. PMID: 23418512 Free PMC article.
Neurotensin/IL-8 pathway orchestrates local inflammatory response and tumor invasion by inducing M2 polarization of Tumor-Associated macrophages and epithelial-mesenchymal transition of hepatocellular carcinoma cells.
Xiao P, Long X, Zhang L, Ye Y, Guo J, Liu P, Zhang R, Ning J, Yu W, Wei F, Yu J. Xiao P, et al. Among authors: liu p. Oncoimmunology. 2018 Mar 13;7(7):e1440166. doi: 10.1080/2162402X.2018.1440166. eCollection 2018. Oncoimmunology. 2018. PMID: 29900041 Free PMC article.
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