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Page 1
Dietary intervention, but not losartan, completely reverses non-alcoholic steatohepatitis in obese and insulin resistant mice.
Verbeek J, Spincemaille P, Vanhorebeek I, Van den Berghe G, Vander Elst I, Windmolders P, van Pelt J, van der Merwe S, Bedossa P, Nevens F, Cammue B, Thevissen K, Cassiman D. Verbeek J, et al. Among authors: bedossa p. Lipids Health Dis. 2017 Feb 23;16(1):46. doi: 10.1186/s12944-017-0432-7. Lipids Health Dis. 2017. PMID: 28231800 Free PMC article.
Lack of efficacy of an inhibitor of PDE4 in phase 1 and 2 trials of patients with nonalcoholic steatohepatitis.
Ratziu V, Bedossa P, Francque SM, Larrey D, Aithal GP, Serfaty L, Voiculescu M, Preotescu L, Nevens F, De Lédinghen V, Kirchner GI, Trunecka P, Ryder SD, Day CP, Takeda J, Traudtner K. Ratziu V, et al. Among authors: bedossa p. Clin Gastroenterol Hepatol. 2014 Oct;12(10):1724-30.e5. doi: 10.1016/j.cgh.2014.01.040. Epub 2014 Feb 12. Clin Gastroenterol Hepatol. 2014. PMID: 24530600 Clinical Trial.
Roux-en-y gastric bypass attenuates hepatic mitochondrial dysfunction in mice with non-alcoholic steatohepatitis.
Verbeek J, Lannoo M, Pirinen E, Ryu D, Spincemaille P, Vander Elst I, Windmolders P, Thevissen K, Cammue BP, van Pelt J, Fransis S, Van Eyken P, Ceuterick-De Groote C, Van Veldhoven PP, Bedossa P, Nevens F, Auwerx J, Cassiman D. Verbeek J, et al. Among authors: bedossa p. Gut. 2015 Apr;64(4):673-83. doi: 10.1136/gutjnl-2014-306748. Epub 2014 Jun 10. Gut. 2015. PMID: 24917551
At similar weight loss, dietary composition determines the degree of glycemic improvement in diet-induced obese C57BL/6 mice.
Vangoitsenhoven R, van der Ende M, Corbeels K, Monteiro Carvalho Mori Cunha JP, Lannoo M, Bedossa P, van der Merwe S, Mertens A, Gesquiere I, Meulemans A, Matthys C, Mathieu C, Overbergh L, Van der Schueren B. Vangoitsenhoven R, et al. Among authors: bedossa p. PLoS One. 2018 Jul 23;13(7):e0200779. doi: 10.1371/journal.pone.0200779. eCollection 2018. PLoS One. 2018. PMID: 30036374 Free PMC article.
Prospective external validation of a new non-invasive test for the diagnosis of non-alcoholic steatohepatitis in patients with type 2 diabetes.
Poynard T, Paradis V, Mullaert J, Deckmyn O, Gault N, Marcault E, Manchon P, Si Mohammed N, Parfait B, Ibberson M, Gautier JF, Boitard C, Czernichow S, Larger E, Drane F, Castille JM, Peta V, Brzustowski A, Terris B, Vallet-Pichard A, Roulot D, Laouénan C, Bedossa P, Castera L, Pol S, Valla D; Quid-Nash consortium. Poynard T, et al. Among authors: bedossa p. Aliment Pharmacol Ther. 2021 Oct;54(7):952-966. doi: 10.1111/apt.16543. Epub 2021 Aug 16. Aliment Pharmacol Ther. 2021. PMID: 34398492 Free PMC article.
C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients.
Zimmermann E, Anty R, Tordjman J, Verrijken A, Gual P, Tran A, Iannelli A, Gugenheim J, Bedossa P, Francque S, Le Marchand-Brustel Y, Clement K, Van Gaal L, Sørensen TIA, Jess T. Zimmermann E, et al. Among authors: bedossa p. J Hepatol. 2011 Sep;55(3):660-665. doi: 10.1016/j.jhep.2010.12.017. Epub 2011 Jan 14. J Hepatol. 2011. PMID: 21238518
Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression.
Loyer X, Paradis V, Hénique C, Vion AC, Colnot N, Guerin CL, Devue C, On S, Scetbun J, Romain M, Paul JL, Rothenberg ME, Marcellin P, Durand F, Bedossa P, Prip-Buus C, Baugé E, Staels B, Boulanger CM, Tedgui A, Rautou PE. Loyer X, et al. Among authors: bedossa p. Gut. 2016 Nov;65(11):1882-1894. doi: 10.1136/gutjnl-2014-308883. Epub 2015 Sep 3. Gut. 2016. PMID: 26338827 Free PMC article.
519 results