Heldin CH - Search Results

1

Imatinib increases oxygen delivery in extracellular matrix-rich but not in matrix-poor experimental carcinoma.

Burmakin M, van Wieringen T, Olsson PO, Stuhr L, Åhgren A, Heldin CH, Reed RK, Rubin K, Hellberg C. Burmakin M, et al. Among authors: heldin ch. J Transl Med. 2017 Feb 23;15(1):47. doi: 10.1186/s12967-017-1142-7. J Transl Med. 2017. PMID: 28231806 Free PMC article.

2

Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy.

Pietras K, Rubin K, Sjöblom T, Buchdunger E, Sjöquist M, Heldin CH, Ostman A. Pietras K, et al. Among authors: heldin ch. Cancer Res. 2002 Oct 1;62(19):5476-84. Cancer Res. 2002. PMID: 12359756

3

PDGF receptors as cancer drug targets.

Pietras K, Sjöblom T, Rubin K, Heldin CH, Ostman A. Pietras K, et al. Among authors: heldin ch. Cancer Cell. 2003 May;3(5):439-43. doi: 10.1016/s1535-6108(03)00089-8. Cancer Cell. 2003. PMID: 12781361 Free article. Review. No abstract available.

4

STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake.

Pietras K, Stumm M, Hubert M, Buchdunger E, Rubin K, Heldin CH, McSheehy P, Wartmann M, Ostman A. Pietras K, et al. Among authors: heldin ch. Clin Cancer Res. 2003 Sep 1;9(10 Pt 1):3779-87. Clin Cancer Res. 2003. PMID: 14506171

5

Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase.

Persson C, Sävenhed C, Bourdeau A, Tremblay ML, Markova B, Böhmer FD, Haj FG, Neel BG, Elson A, Heldin CH, Rönnstrand L, Ostman A, Hellberg C. Persson C, et al. Among authors: heldin ch. Mol Cell Biol. 2004 Mar;24(5):2190-201. doi: 10.1128/MCB.24.5.2190-2201.2004. Mol Cell Biol. 2004. PMID: 14966296 Free PMC article.

6

A gain of function mutation in the activation loop of platelet-derived growth factor beta-receptor deregulates its kinase activity.

Chiara F, Goumans MJ, Forsberg H, Ahgrén A, Rasola A, Aspenström P, Wernstedt C, Hellberg C, Heldin CH, Heuchel R. Chiara F, et al. Among authors: heldin ch. J Biol Chem. 2004 Oct 8;279(41):42516-27. doi: 10.1074/jbc.M406051200. Epub 2004 Jul 28. J Biol Chem. 2004. PMID: 15284236 Free article.

7

High interstitial fluid pressure - an obstacle in cancer therapy.

Heldin CH, Rubin K, Pietras K, Ostman A. Heldin CH, et al. Nat Rev Cancer. 2004 Oct;4(10):806-13. doi: 10.1038/nrc1456. Nat Rev Cancer. 2004. PMID: 15510161 Review.

8

Deletion of exon I of SMAD7 in mice results in altered B cell responses.

Li R, Rosendahl A, Brodin G, Cheng AM, Ahgren A, Sundquist C, Kulkarni S, Pawson T, Heldin CH, Heuchel RL. Li R, et al. Among authors: heldin ch. J Immunol. 2006 Jun 1;176(11):6777-84. doi: 10.4049/jimmunol.176.11.6777. J Immunol. 2006. PMID: 16709837

9

Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) beta-receptor but not the PDGF alpha-receptor.

Karlsson S, Kowanetz K, Sandin A, Persson C, Ostman A, Heldin CH, Hellberg C. Karlsson S, et al. Among authors: heldin ch. Mol Biol Cell. 2006 Nov;17(11):4846-55. doi: 10.1091/mbc.e06-04-0306. Epub 2006 Sep 13. Mol Biol Cell. 2006. PMID: 16971512 Free PMC article.

10

An activating mutation in the PDGF receptor-beta causes abnormal morphology in the mouse placenta.

Looman C, Sun T, Yu Y, Zieba A, Ahgren A, Feinstein R, Forsberg H, Hellberg C, Heldin CH, Zhang XQ, Forsberg-Nilsson K, Khoo N, Fundele R, Heuchel R. Looman C, et al. Among authors: heldin ch. Int J Dev Biol. 2007;51(5):361-70. doi: 10.1387/ijdb.072301cl. Int J Dev Biol. 2007. PMID: 17616925 Free article.

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