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KLF2 and KLF4 control endothelial identity and vascular integrity.
Sangwung P, Zhou G, Nayak L, Chan ER, Kumar S, Kang DW, Zhang R, Liao X, Lu Y, Sugi K, Fujioka H, Shi H, Lapping SD, Ghosh CC, Higgins SJ, Parikh SM, Jo H, Jain MK. Sangwung P, et al. Among authors: zhou g. JCI Insight. 2017 Feb 23;2(4):e91700. doi: 10.1172/jci.insight.91700. JCI Insight. 2017. PMID: 28239661 Free PMC article.
The myeloid transcription factor KLF2 regulates the host response to polymicrobial infection and endotoxic shock.
Mahabeleshwar GH, Kawanami D, Sharma N, Takami Y, Zhou G, Shi H, Nayak L, Jeyaraj D, Grealy R, White M, McManus R, Ryan T, Leahy P, Lin Z, Haldar SM, Atkins GB, Wong HR, Lingrel JB, Jain MK. Mahabeleshwar GH, et al. Among authors: zhou g. Immunity. 2011 May 27;34(5):715-28. doi: 10.1016/j.immuni.2011.04.014. Epub 2011 May 12. Immunity. 2011. PMID: 21565532 Free PMC article.
Krüppel-like factor 4 regulates macrophage polarization.
Liao X, Sharma N, Kapadia F, Zhou G, Lu Y, Hong H, Paruchuri K, Mahabeleshwar GH, Dalmas E, Venteclef N, Flask CA, Kim J, Doreian BW, Lu KQ, Kaestner KH, Hamik A, Clément K, Jain MK. Liao X, et al. Among authors: zhou g. J Clin Invest. 2011 Jul;121(7):2736-49. doi: 10.1172/JCI45444. Epub 2011 Jun 13. J Clin Invest. 2011. PMID: 21670502 Free PMC article.
Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice.
Zhou G, Hamik A, Nayak L, Tian H, Shi H, Lu Y, Sharma N, Liao X, Hale A, Boerboom L, Feaver RE, Gao H, Desai A, Schmaier A, Gerson SL, Wang Y, Atkins GB, Blackman BR, Simon DI, Jain MK. Zhou G, et al. J Clin Invest. 2012 Dec;122(12):4727-31. doi: 10.1172/JCI66056. Epub 2012 Nov 19. J Clin Invest. 2012. PMID: 23160196 Free PMC article.
Kruppel-like factor 15 is critical for vascular inflammation.
Lu Y, Zhang L, Liao X, Sangwung P, Prosdocimo DA, Zhou G, Votruba AR, Brian L, Han YJ, Gao H, Wang Y, Shimizu K, Weinert-Stein K, Khrestian M, Simon DI, Freedman NJ, Jain MK. Lu Y, et al. Among authors: zhou g. J Clin Invest. 2013 Oct;123(10):4232-41. doi: 10.1172/JCI68552. Epub 2013 Sep 3. J Clin Invest. 2013. PMID: 23999430 Free PMC article.
Endothelial Krüppel-like factor 4 modulates pulmonary arterial hypertension.
Shatat MA, Tian H, Zhang R, Tandon G, Hale A, Fritz JS, Zhou G, Martínez-González J, Rodríguez C, Champion HC, Jain MK, Hamik A. Shatat MA, et al. Among authors: zhou g. Am J Respir Cell Mol Biol. 2014 Mar;50(3):647-53. doi: 10.1165/rcmb.2013-0135OC. Am J Respir Cell Mol Biol. 2014. PMID: 24156273 Free PMC article.
Circadian control of bile acid synthesis by a KLF15-Fgf15 axis.
Han S, Zhang R, Jain R, Shi H, Zhang L, Zhou G, Sangwung P, Tugal D, Atkins GB, Prosdocimo DA, Lu Y, Han X, Tso P, Liao X, Epstein JA, Jain MK. Han S, et al. Among authors: zhou g. Nat Commun. 2015 Jun 4;6:7231. doi: 10.1038/ncomms8231. Nat Commun. 2015. PMID: 26040986 Free PMC article.
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