Ledgerwood EC - Search Results

1

Structural basis of autoregulatory scaffolding by apoptosis signal-regulating kinase 1.

Weijman JF, Kumar A, Jamieson SA, King CM, Caradoc-Davies TT, Ledgerwood EC, Murphy JM, Mace PD. Weijman JF, et al. Among authors: ledgerwood ec. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2096-E2105. doi: 10.1073/pnas.1620813114. Epub 2017 Feb 27. Proc Natl Acad Sci U S A. 2017. PMID: 28242696 Free PMC article.

2

Peroxiredoxin 1 functions as a signal peroxidase to receive, transduce, and transmit peroxide signals in mammalian cells.

Jarvis RM, Hughes SM, Ledgerwood EC. Jarvis RM, et al. Among authors: ledgerwood ec. Free Radic Biol Med. 2012 Oct 1;53(7):1522-30. doi: 10.1016/j.freeradbiomed.2012.08.001. Epub 2012 Aug 8. Free Radic Biol Med. 2012. PMID: 22902630

3

The role of peroxiredoxin 1 in redox sensing and transducing.

Ledgerwood EC, Marshall JW, Weijman JF. Ledgerwood EC, et al. Arch Biochem Biophys. 2017 Mar 1;617:60-67. doi: 10.1016/j.abb.2016.10.009. Epub 2016 Oct 15. Arch Biochem Biophys. 2017. PMID: 27756681 Review.

4

The Structure and Ubiquitin Binding Properties of TRAF RING Heterodimers.

Das A, Middleton AJ, Padala P, Ledgerwood EC, Mace PD, Day CL. Das A, et al. Among authors: ledgerwood ec. J Mol Biol. 2021 Apr 16;433(8):166844. doi: 10.1016/j.jmb.2021.166844. Epub 2021 Feb 2. J Mol Biol. 2021. PMID: 33539883

5

CYCS gene variants associated with thrombocytopenia.

Ledgerwood EC, Dunstan-Harrison C, Ong L, Morison IM. Ledgerwood EC, et al. Platelets. 2019;30(5):672-674. doi: 10.1080/09537104.2018.1543866. Epub 2018 Nov 19. Platelets. 2019. PMID: 30452302 Free article. No abstract available.

6

Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity.

Fellner M, Parakra R, McDonald KO, Kass I, Jameson GNL, Wilbanks SM, Ledgerwood EC. Fellner M, et al. Among authors: ledgerwood ec. Biochem J. 2021 Feb 12;478(3):669-684. doi: 10.1042/BCJ20200793. Biochem J. 2021. PMID: 33480393

7

Conformational change and human cytochrome c function: mutation of residue 41 modulates caspase activation and destabilizes Met-80 coordination.

Josephs TM, Liptak MD, Hughes G, Lo A, Smith RM, Wilbanks SM, Bren KL, Ledgerwood EC. Josephs TM, et al. Among authors: ledgerwood ec. J Biol Inorg Chem. 2013 Mar;18(3):289-97. doi: 10.1007/s00775-012-0973-1. Epub 2013 Jan 19. J Biol Inorg Chem. 2013. PMID: 23334161 Free PMC article.

8

The imprinted gene Peg3 is not essential for tumor necrosis factor alpha signaling.

Ledgerwood EC, O'Rahilly S, Surani MA. Ledgerwood EC, et al. Lab Invest. 2000 Oct;80(10):1509-11. doi: 10.1038/labinvest.3780160. Lab Invest. 2000. PMID: 11045567 Free article.

9

A novel Bcl-2-like inhibitor of apoptosis is encoded by the parapoxvirus ORF virus.

Westphal D, Ledgerwood EC, Hibma MH, Fleming SB, Whelan EM, Mercer AA. Westphal D, et al. Among authors: ledgerwood ec. J Virol. 2007 Jul;81(13):7178-88. doi: 10.1128/JVI.00404-07. Epub 2007 May 2. J Virol. 2007. PMID: 17475653 Free PMC article.

10

The orf virus inhibitor of apoptosis functions in a Bcl-2-like manner, binding and neutralizing a set of BH3-only proteins and active Bax.

Westphal D, Ledgerwood EC, Tyndall JD, Hibma MH, Ueda N, Fleming SB, Mercer AA. Westphal D, et al. Among authors: ledgerwood ec. Apoptosis. 2009 Nov;14(11):1317-30. doi: 10.1007/s10495-009-0403-1. Apoptosis. 2009. PMID: 19779821

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