Forman-Kay JD - Search Results

1

Synergy of cAMP and calcium signaling pathways in CFTR regulation.

Bozoky Z, Ahmadi S, Milman T, Kim TH, Du K, Di Paola M, Pasyk S, Pekhletski R, Keller JP, Bear CE, Forman-Kay JD. Bozoky Z, et al. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2086-E2095. doi: 10.1073/pnas.1613546114. Epub 2017 Feb 27. Proc Natl Acad Sci U S A. 2017. PMID: 28242698 Free PMC article.

2

Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide.

Donaldson LW, Gish G, Pawson T, Kay LE, Forman-Kay JD. Donaldson LW, et al. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14053-8. doi: 10.1073/pnas.212518799. Epub 2002 Oct 16. Proc Natl Acad Sci U S A. 2002. PMID: 12384576 Free PMC article.

3

Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity.

Borg M, Mittag T, Pawson T, Tyers M, Forman-Kay JD, Chan HS. Borg M, et al. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9650-5. doi: 10.1073/pnas.0702580104. Epub 2007 May 23. Proc Natl Acad Sci U S A. 2007. PMID: 17522259 Free PMC article.

4

CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices.

Baker JM, Hudson RP, Kanelis V, Choy WY, Thibodeau PH, Thomas PJ, Forman-Kay JD. Baker JM, et al. Nat Struct Mol Biol. 2007 Aug;14(8):738-45. doi: 10.1038/nsmb1278. Epub 2007 Jul 29. Nat Struct Mol Biol. 2007. PMID: 17660831 Free PMC article.

5

Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor.

Mittag T, Orlicky S, Choy WY, Tang X, Lin H, Sicheri F, Kay LE, Tyers M, Forman-Kay JD. Mittag T, et al. Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17772-7. doi: 10.1073/pnas.0809222105. Epub 2008 Nov 13. Proc Natl Acad Sci U S A. 2008. PMID: 19008353 Free PMC article.

6

NMR evidence for differential phosphorylation-dependent interactions in WT and DeltaF508 CFTR.

Kanelis V, Hudson RP, Thibodeau PH, Thomas PJ, Forman-Kay JD. Kanelis V, et al. EMBO J. 2010 Jan 6;29(1):263-77. doi: 10.1038/emboj.2009.329. Epub 2009 Nov 19. EMBO J. 2010. PMID: 19927121 Free PMC article.

7

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity.

Chong PA, Lin H, Wrana JL, Forman-Kay JD. Chong PA, et al. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18404-9. doi: 10.1073/pnas.1003023107. Epub 2010 Oct 11. Proc Natl Acad Sci U S A. 2010. PMID: 20937913 Free PMC article.

8

NMR spectroscopy to study the dynamics and interactions of CFTR.

Kanelis V, Chong PA, Forman-Kay JD. Kanelis V, et al. Methods Mol Biol. 2011;741:377-403. doi: 10.1007/978-1-61779-117-8_25. Methods Mol Biol. 2011. PMID: 21594798

9

Phosphorylation-dependent 14-3-3 protein interactions regulate CFTR biogenesis.

Liang X, Da Paula AC, Bozóky Z, Zhang H, Bertrand CA, Peters KW, Forman-Kay JD, Frizzell RA. Liang X, et al. Mol Biol Cell. 2012 Mar;23(6):996-1009. doi: 10.1091/mbc.E11-08-0662. Epub 2012 Jan 25. Mol Biol Cell. 2012. PMID: 22278744 Free PMC article.

10

Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator.

Hudson RP, Chong PA, Protasevich II, Vernon R, Noy E, Bihler H, An JL, Kalid O, Sela-Culang I, Mense M, Senderowitz H, Brouillette CG, Forman-Kay JD. Hudson RP, et al. J Biol Chem. 2012 Aug 17;287(34):28480-94. doi: 10.1074/jbc.M112.371138. Epub 2012 Jun 21. J Biol Chem. 2012. PMID: 22722932 Free PMC article.

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