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Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension.
Houssaini A, Abid S, Derumeaux G, Wan F, Parpaleix A, Rideau D, Marcos E, Kebe K, Czibik G, Sawaki D, Treins C, Dubois-Randé JL, Li Z, Amsellem V, Lipskaia L, Pende M, Adnot S. Houssaini A, et al. Among authors: treins c. Am J Respir Cell Mol Biol. 2016 Sep;55(3):352-67. doi: 10.1165/rcmb.2015-0339OC. Am J Respir Cell Mol Biol. 2016. PMID: 26991739
Rictor is a novel target of p70 S6 kinase-1.
Treins C, Warne PH, Magnuson MA, Pende M, Downward J. Treins C, et al. Oncogene. 2010 Feb 18;29(7):1003-16. doi: 10.1038/onc.2009.401. Epub 2009 Nov 23. Oncogene. 2010. PMID: 19935711
Depdc5 knockout rat: A novel model of mTORopathy.
Marsan E, Ishida S, Schramm A, Weckhuysen S, Muraca G, Lecas S, Liang N, Treins C, Pende M, Roussel D, Le Van Quyen M, Mashimo T, Kaneko T, Yamamoto T, Sakuma T, Mahon S, Miles R, Leguern E, Charpier S, Baulac S. Marsan E, et al. Among authors: treins c. Neurobiol Dis. 2016 May;89:180-9. doi: 10.1016/j.nbd.2016.02.010. Epub 2016 Feb 9. Neurobiol Dis. 2016. PMID: 26873552 Free article.
AKT2 is essential to maintain podocyte viability and function during chronic kidney disease.
Canaud G, Bienaimé F, Viau A, Treins C, Baron W, Nguyen C, Burtin M, Berissi S, Giannakakis K, Muda AO, Zschiedrich S, Huber TB, Friedlander G, Legendre C, Pontoglio M, Pende M, Terzi F. Canaud G, et al. Among authors: treins c. Nat Med. 2013 Oct;19(10):1288-96. doi: 10.1038/nm.3313. Epub 2013 Sep 22. Nat Med. 2013. PMID: 24056770
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