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Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer.
Jansen VM, Bhola NE, Bauer JA, Formisano L, Lee KM, Hutchinson KE, Witkiewicz AK, Moore PD, Estrada MV, Sánchez V, Ericsson PG, Sanders ME, Pohlmann PR, Pishvaian MJ, Riddle DA, Dugger TC, Wei W, Knudsen ES, Arteaga CL. Jansen VM, et al. Among authors: knudsen es. Cancer Res. 2017 May 1;77(9):2488-2499. doi: 10.1158/0008-5472.CAN-16-2653. Epub 2017 Mar 1. Cancer Res. 2017. PMID: 28249908 Free PMC article.
Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy.
Mercier I, Casimiro MC, Wang C, Rosenberg AL, Quong J, Minkeu A, Allen KG, Danilo C, Sotgia F, Bonuccelli G, Jasmin JF, Xu H, Bosco E, Aronow B, Witkiewicz A, Pestell RG, Knudsen ES, Lisanti MP. Mercier I, et al. Among authors: knudsen es. Cancer Biol Ther. 2008 Aug;7(8):1212-25. doi: 10.4161/cbt.7.8.6220. Epub 2008 Aug 30. Cancer Biol Ther. 2008. PMID: 18458534 Free PMC article.
Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.
Sotgia F, Del Galdo F, Casimiro MC, Bonuccelli G, Mercier I, Whitaker-Menezes D, Daumer KM, Zhou J, Wang C, Katiyar S, Xu H, Bosco E, Quong AA, Aronow B, Witkiewicz AK, Minetti C, Frank PG, Jimenez SA, Knudsen ES, Pestell RG, Lisanti MP. Sotgia F, et al. Among authors: knudsen es. Am J Pathol. 2009 Mar;174(3):746-61. doi: 10.2353/ajpath.2009.080658. Am J Pathol. 2009. PMID: 19234134 Free PMC article.
Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome.
Millar EK, Dean JL, McNeil CM, O'Toole SA, Henshall SM, Tran T, Lin J, Quong A, Comstock CE, Witkiewicz A, Musgrove EA, Rui H, Lemarchand L, Setiawan VW, Haiman CA, Knudsen KE, Sutherland RL, Knudsen ES. Millar EK, et al. Among authors: knudsen ke, knudsen es. Oncogene. 2009 Apr 16;28(15):1812-20. doi: 10.1038/onc.2009.13. Epub 2009 Mar 16. Oncogene. 2009. PMID: 19287456 Free PMC article.
Targeting the RB-pathway in cancer therapy.
Knudsen ES, Wang JY. Knudsen ES, et al. Clin Cancer Res. 2010 Feb 15;16(4):1094-9. doi: 10.1158/1078-0432.CCR-09-0787. Epub 2010 Feb 9. Clin Cancer Res. 2010. PMID: 20145169 Free PMC article.
200 results