Hazlitt RA - Search Results

1

Effect of Substituents and Stability of Transient Aluminum-Aminals in the Presence of Nucleophiles.

Barrios FJ, Springer BC, Hazlitt RA, Colby DA. Barrios FJ, et al. Among authors: hazlitt ra. Synthesis (Stuttg). 2015 Jan;47(2):175-180. doi: 10.1055/s-0034-1379635. Epub 2014 Dec 5. Synthesis (Stuttg). 2015. PMID: 28250502 Free PMC article.

2

Optimized Synthesis of a Pentafluoro-gem-diol and Conversion to a CF₂Br-Glucopyranose through Trifluoroacetate-Release and Halogenation.

Hazlitt RA, John JP, Tran QL, Colby DA. Hazlitt RA, et al. Tetrahedron Lett. 2016 Apr 27;57(17):1906-1908. doi: 10.1016/j.tetlet.2016.03.064. Epub 2016 Mar 19. Tetrahedron Lett. 2016. PMID: 27182091 Free PMC article.

3

Generation of Magnesium Pentafluoropropen-2-olate from Hexafluoroisopropanol and Synthesis of 2,2,4,4,4-Pentafluoro-3,3-dihydroxyketones.

Hazlitt RA, Tran QL, Sowaileh MF, Colby DA. Hazlitt RA, et al. J Org Chem. 2017 Feb 17;82(4):2231-2236. doi: 10.1021/acs.joc.6b02863. Epub 2017 Jan 31. J Org Chem. 2017. PMID: 28107014 Free PMC article.

4

Conversion of Methyl Ketones and Methyl Sulfones into α-Deutero-α,α-Difluoromethyl Ketones and α-Deutero-α,α-Difluoromethyl Sulfones in Three Synthetic Steps.

Sowaileh MF, Han C, Hazlitt RA, Kim EH, John JP, Colby DA. Sowaileh MF, et al. Among authors: hazlitt ra. Tetrahedron Lett. 2017 Feb 1;58(5):396-400. doi: 10.1016/j.tetlet.2016.12.018. Epub 2016 Dec 21. Tetrahedron Lett. 2017. PMID: 28943667 Free PMC article.

5

Application of the Pentafluorosulfanyl Group as a Bioisosteric Replacement.

Sowaileh MF, Hazlitt RA, Colby DA. Sowaileh MF, et al. Among authors: hazlitt ra. ChemMedChem. 2017 Sep 21;12(18):1481-1490. doi: 10.1002/cmdc.201700356. Epub 2017 Sep 14. ChemMedChem. 2017. PMID: 28782186 Review.

6

CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss.

Teitz T, Fang J, Goktug AN, Bonga JD, Diao S, Hazlitt RA, Iconaru L, Morfouace M, Currier D, Zhou Y, Umans RA, Taylor MR, Cheng C, Min J, Freeman B, Peng J, Roussel MF, Kriwacki R, Guy RK, Chen T, Zuo J. Teitz T, et al. Among authors: hazlitt ra. J Exp Med. 2018 Apr 2;215(4):1187-1203. doi: 10.1084/jem.20172246. Epub 2018 Mar 7. J Exp Med. 2018. PMID: 29514916 Free PMC article.

7

AZD5438-PROTAC: A selective CDK2 degrader that protects against cisplatin- and noise-induced hearing loss.

Hati S, Zallocchi M, Hazlitt R, Li Y, Vijayakumar S, Min J, Rankovic Z, Lovas S, Zuo J. Hati S, et al. Eur J Med Chem. 2021 Dec 15;226:113849. doi: 10.1016/j.ejmech.2021.113849. Epub 2021 Sep 20. Eur J Med Chem. 2021. PMID: 34560429 Free PMC article.

8

Progress in the Development of Preventative Drugs for Cisplatin-Induced Hearing Loss.

Hazlitt RA, Min J, Zuo J. Hazlitt RA, et al. J Med Chem. 2018 Jul 12;61(13):5512-5524. doi: 10.1021/acs.jmedchem.7b01653. Epub 2018 Feb 1. J Med Chem. 2018. PMID: 29361217 Free PMC article. Review.

9

Development of Second-Generation CDK2 Inhibitors for the Prevention of Cisplatin-Induced Hearing Loss.

Hazlitt RA, Teitz T, Bonga JD, Fang J, Diao S, Iconaru L, Yang L, Goktug AN, Currier DG, Chen T, Rankovic Z, Min J, Zuo J. Hazlitt RA, et al. J Med Chem. 2018 Sep 13;61(17):7700-7709. doi: 10.1021/acs.jmedchem.8b00669. Epub 2018 Aug 24. J Med Chem. 2018. PMID: 30091915 Free PMC article.

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