Guy RK - Search Results

1

Shared Consensus Machine Learning Models for Predicting Blood Stage Malaria Inhibition.

Verras A, Waller CL, Gedeck P, Green DV, Kogej T, Raichurkar A, Panda M, Shelat AA, Clark J, Guy RK, Papadatos G, Burrows J. Verras A, et al. Among authors: guy rk. J Chem Inf Model. 2017 Mar 27;57(3):445-453. doi: 10.1021/acs.jcim.6b00572. Epub 2017 Mar 17. J Chem Inf Model. 2017. PMID: 28257198

2

A solid-phase approach to the phallotoxins: total synthesis of [Ala7]-phalloidin.

Anderson MO, Shelat AA, Guy RK. Anderson MO, et al. Among authors: guy rk. J Org Chem. 2005 Jun 10;70(12):4578-84. doi: 10.1021/jo0503153. J Org Chem. 2005. PMID: 15932292

3

A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding.

Arnold LA, Estébanez-Perpiñá E, Togashi M, Shelat A, Ocasio CA, McReynolds AC, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK. Arnold LA, et al. Among authors: guy rk. Sci STKE. 2006 Jun 27;2006(341):pl3. doi: 10.1126/stke.3412006pl3. Sci STKE. 2006. PMID: 16804159

4

Searching for new antimalarial therapeutics amongst known drugs.

Weisman JL, Liou AP, Shelat AA, Cohen FE, Guy RK, DeRisi JL. Weisman JL, et al. Among authors: guy rk. Chem Biol Drug Des. 2006 Jun;67(6):409-16. doi: 10.1111/j.1747-0285.2006.00391.x. Chem Biol Drug Des. 2006. PMID: 16882315 Free PMC article.

5

Design of a selective chemical probe for class I PDZ domains.

Fujii N, Shelat A, Hall RA, Guy RK. Fujii N, et al. Among authors: guy rk. Bioorg Med Chem Lett. 2007 Jan 15;17(2):546-8. doi: 10.1016/j.bmcl.2006.10.027. Epub 2006 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17074480

6

The interdependence between screening methods and screening libraries.

Shelat AA, Guy RK. Shelat AA, et al. Among authors: guy rk. Curr Opin Chem Biol. 2007 Jun;11(3):244-51. doi: 10.1016/j.cbpa.2007.05.003. Epub 2007 May 23. Curr Opin Chem Biol. 2007. PMID: 17524728 Review.

7

Scaffold composition and biological relevance of screening libraries.

Shelat AA, Guy RK. Shelat AA, et al. Among authors: guy rk. Nat Chem Biol. 2007 Aug;3(8):442-6. doi: 10.1038/nchembio0807-442. Nat Chem Biol. 2007. PMID: 17637770

8

Assay Optimization and Screening of RNA-Protein Interactions by AlphaScreen.

Mills NL, Shelat AA, Guy RK. Mills NL, et al. Among authors: guy rk. J Biomol Screen. 2007 Oct;12(7):946-55. doi: 10.1177/1087057107306128. J Biomol Screen. 2007. PMID: 17942787

9

Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

Mallari JP, Shelat AA, Obrien T, Caffrey CR, Kosinski A, Connelly M, Harbut M, Greenbaum D, McKerrow JH, Guy RK. Mallari JP, et al. Among authors: guy rk. J Med Chem. 2008 Feb 14;51(3):545-52. doi: 10.1021/jm070760l. Epub 2008 Jan 4. J Med Chem. 2008. PMID: 18173229

10

A road less traveled by: exploring a decade of Ellman chemistry.

Shelat AA, Guy RK. Shelat AA, et al. Among authors: guy rk. Bioorg Med Chem. 2009 Feb 1;17(3):1088-93. doi: 10.1016/j.bmc.2008.02.087. Epub 2008 Mar 4. Bioorg Med Chem. 2009. PMID: 18343129 Free PMC article.

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