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Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing.
Li J, Stagg NJ, Johnston J, Harris MJ, Menzies SA, DiCara D, Clark V, Hristopoulos M, Cook R, Slaga D, Nakamura R, McCarty L, Sukumaran S, Luis E, Ye Z, Wu TD, Sumiyoshi T, Danilenko D, Lee GY, Totpal K, Ellerman D, Hötzel I, James JR, Junttila TT. Li J, et al. Among authors: johnston j. Cancer Cell. 2017 Mar 13;31(3):383-395. doi: 10.1016/j.ccell.2017.02.001. Epub 2017 Mar 2. Cancer Cell. 2017. PMID: 28262555 Free PMC article.
Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells.
Junttila TT, Li J, Johnston J, Hristopoulos M, Clark R, Ellerman D, Wang BE, Li Y, Mathieu M, Li G, Young J, Luis E, Lewis Phillips G, Stefanich E, Spiess C, Polson A, Irving B, Scheer JM, Junttila MR, Dennis MS, Kelley R, Totpal K, Ebens A. Junttila TT, et al. Among authors: johnston j. Cancer Res. 2014 Oct 1;74(19):5561-71. doi: 10.1158/0008-5472.CAN-13-3622-T. Epub 2014 Sep 16. Cancer Res. 2014. PMID: 25228655
Target arm affinities determine preclinical efficacy and safety of anti-HER2/CD3 bispecific antibody.
Staflin K, Zuch de Zafra CL, Schutt LK, Clark V, Zhong F, Hristopoulos M, Clark R, Li J, Mathieu M, Chen X, Johnston J, Low J, Ybarra R, Slaga D, Yang J, Ovacik M, Dybdal NO, Totpal K, Junttila MR, Ellerman D, Lee G, Dennis MS, Prell R, Junttila TT. Staflin K, et al. Among authors: johnston j. JCI Insight. 2020 Apr 9;5(7):e133757. doi: 10.1172/jci.insight.133757. JCI Insight. 2020. PMID: 32271166 Free PMC article.
Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer.
Lo AA, Johnston J, Li J, Mandikian D, Hristopoulos M, Clark R, Nickles D, Liang WC, Hötzel K, Dunlap D, Pham T, Cai H, Ovacik M, Bravo-Perez D, Mai E, Slaga D, Ellerman D, Ziai J, Totpal K, Lee G, Boswell CA, Payandeh J, Wu Y, Junttila TT. Lo AA, et al. Among authors: johnston j. Mol Cancer Ther. 2021 Apr;20(4):716-725. doi: 10.1158/1535-7163.MCT-20-0490. Epub 2021 Feb 3. Mol Cancer Ther. 2021. PMID: 33536191
Expanding the Agenda for a More Just Genomics.
Dolan DD, Pacia DM, Johnston J, Lee SS, Cho MK. Dolan DD, et al. Among authors: johnston j. Hastings Cent Rep. 2024 Dec;54 Suppl 2:S2-S13. doi: 10.1002/hast.4924. Hastings Cent Rep. 2024. PMID: 39707954
One term to transform: universal health coverage through professional community health workers.
Ballard M, Dahn B, O'Donovan J, Jiménez A, Kawooya P, Raghavan M, Ganjian N, Johnson AD, Boxer C, Gray K, Palazuelos D, Berry-Moorcroft C, Aranda Z, Iberico MM, Cordier L, Mbewe D, Yegon EK, Ernst J, DiStefano L, Traill T, Finnegan KE, Rakotonirina L, Hofmann R, Sano ED, Johnston JS, Ward V, Westgate C, Shanmugarasa T, Alban R, Mann D, Asmara-Petersen R, Keronyai P, Settle D, Aidam J, Obbuyi A, Oladeji O, Muyingo P, Cho K, Kok M. Ballard M, et al. Among authors: johnston js. Lancet. 2024 Dec 11:S0140-6736(24)02713-2. doi: 10.1016/S0140-6736(24)02713-2. Online ahead of print. Lancet. 2024. PMID: 39674183 No abstract available.
4,312 results