The effect of long-term bisphosphonate therapy on trabecular bone strength and microcrack density.
Jin A, Cobb J, Hansen U, Bhattacharya R, Reinhard C, Vo N, Atwood R, Li J, Karunaratne A, Wiles C, Abel R.
Jin A, et al.
Bone Joint Res. 2017 Oct;6(10):602-609. doi: 10.1302/2046-3758.610.BJR-2016-0321.R1.
Bone Joint Res. 2017.
PMID: 29066534
Free PMC article.
This low strength may be due to the greater accumulation of microcracks and a lack of any discernible improvement in bone volume or microarchitecture. This preliminary study suggests that the clinical impact of BP-induced microcrack accumulation may be significant.Cite thi …
This low strength may be due to the greater accumulation of microcracks and a lack of any discernible improvement in bone volume or m …