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CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus.
Faridi MH, Khan SQ, Zhao W, Lee HW, Altintas MM, Zhang K, Kumar V, Armstrong AR, Carmona-Rivera C, Dorschner JM, Schnaith AM, Li X, Ghodke-Puranik Y, Moore E, Purmalek M, Irizarry-Caro J, Zhang T, Day R, Stoub D, Hoffmann V, Khaliqdina SJ, Bhargava P, Santander AM, Torroella-Kouri M, Issac B, Cimbaluk DJ, Zloza A, Prabhakar R, Deep S, Jolly M, Koh KH, Reichner JS, Bradshaw EM, Chen J, Moita LF, Yuen PS, Li Tsai W, Singh B, Reiser J, Nath SK, Niewold TB, Vazquez-Padron RI, Kaplan MJ, Gupta V. Faridi MH, et al. Among authors: gupta v. J Clin Invest. 2017 Apr 3;127(4):1271-1283. doi: 10.1172/JCI88442. Epub 2017 Mar 6. J Clin Invest. 2017. PMID: 28263189 Free PMC article.
Identification of novel agonists of the integrin CD11b/CD18.
Faridi MH, Maiguel D, Barth CJ, Stoub D, Day R, Schürer S, Gupta V. Faridi MH, et al. Among authors: gupta v. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6902-6. doi: 10.1016/j.bmcl.2009.10.077. Epub 2009 Oct 22. Bioorg Med Chem Lett. 2009. PMID: 19879752 Free PMC article.
Toward the development of podocyte-specific drugs.
Reiser J, Gupta V, Kistler AD. Reiser J, et al. Among authors: gupta v. Kidney Int. 2010 Apr;77(8):662-8. doi: 10.1038/ki.2009.559. Epub 2010 Feb 3. Kidney Int. 2010. PMID: 20130528 Free PMC article. Review.
Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease.
Maiguel D, Faridi MH, Wei C, Kuwano Y, Balla KM, Hernandez D, Barth CJ, Lugo G, Donnelly M, Nayer A, Moita LF, Schürer S, Traver D, Ruiz P, Vazquez-Padron RI, Ley K, Reiser J, Gupta V. Maiguel D, et al. Among authors: gupta v. Sci Signal. 2011 Sep 6;4(189):ra57. doi: 10.1126/scisignal.2001811. Sci Signal. 2011. PMID: 21900205 Free PMC article.
Macrophage-derived IL-18 and increased fibrinogen deposition are age-related inflammatory signatures of vascular remodeling.
Rodriguez-Menocal L, Faridi MH, Martinez L, Shehadeh LA, Duque JC, Wei Y, Mesa A, Pena A, Gupta V, Pham SM, Vazquez-Padron RI. Rodriguez-Menocal L, et al. Among authors: gupta v. Am J Physiol Heart Circ Physiol. 2014 Mar 1;306(5):H641-53. doi: 10.1152/ajpheart.00641.2013. Epub 2014 Jan 10. Am J Physiol Heart Circ Physiol. 2014. PMID: 24414074 Free PMC article.
8,026 results