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CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus.
Faridi MH, Khan SQ, Zhao W, Lee HW, Altintas MM, Zhang K, Kumar V, Armstrong AR, Carmona-Rivera C, Dorschner JM, Schnaith AM, Li X, Ghodke-Puranik Y, Moore E, Purmalek M, Irizarry-Caro J, Zhang T, Day R, Stoub D, Hoffmann V, Khaliqdina SJ, Bhargava P, Santander AM, Torroella-Kouri M, Issac B, Cimbaluk DJ, Zloza A, Prabhakar R, Deep S, Jolly M, Koh KH, Reichner JS, Bradshaw EM, Chen J, Moita LF, Yuen PS, Li Tsai W, Singh B, Reiser J, Nath SK, Niewold TB, Vazquez-Padron RI, Kaplan MJ, Gupta V. Faridi MH, et al. Among authors: khan sq. J Clin Invest. 2017 Apr 3;127(4):1271-1283. doi: 10.1172/JCI88442. Epub 2017 Mar 6. J Clin Invest. 2017. PMID: 28263189 Free PMC article.
A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules.
Lee HW, Khan SQ, Faridi MH, Wei C, Tardi NJ, Altintas MM, Elshabrawy HA, Mangos S, Quick KL, Sever S, Reiser J, Gupta V. Lee HW, et al. Among authors: khan sq. J Am Soc Nephrol. 2015 Nov;26(11):2741-52. doi: 10.1681/ASN.2014090859. Epub 2015 Apr 9. J Am Soc Nephrol. 2015. PMID: 25858967 Free PMC article.
Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1.
Lee HW, Khan SQ, Khaliqdina S, Altintas MM, Grahammer F, Zhao JL, Koh KH, Tardi NJ, Faridi MH, Geraghty T, Cimbaluk DJ, Susztak K, Moita LF, Baltimore D, Tharaux PL, Huber TB, Kretzler M, Bitzer M, Reiser J, Gupta V. Lee HW, et al. Among authors: khan sq. J Biol Chem. 2017 Jan 13;292(2):732-747. doi: 10.1074/jbc.M116.753822. Epub 2016 Dec 2. J Biol Chem. 2017. PMID: 27913625 Free PMC article.
CD11b Activity Modulates Pathogenesis of Lupus Nephritis.
Khan SQ, Khan I, Gupta V. Khan SQ, et al. Among authors: khan i. Front Med (Lausanne). 2018 Mar 15;5:52. doi: 10.3389/fmed.2018.00052. eCollection 2018. Front Med (Lausanne). 2018. PMID: 29600248 Free PMC article. Review.
Integrin CD11b activation drives anti-tumor innate immunity.
Schmid MC, Khan SQ, Kaneda MM, Pathria P, Shepard R, Louis TL, Anand S, Woo G, Leem C, Faridi MH, Geraghty T, Rajagopalan A, Gupta S, Ahmed M, Vazquez-Padron RI, Cheresh DA, Gupta V, Varner JA. Schmid MC, et al. Among authors: khan sq. Nat Commun. 2018 Dec 19;9(1):5379. doi: 10.1038/s41467-018-07387-4. Nat Commun. 2018. PMID: 30568188 Free PMC article.
CD11b suppresses TLR7-driven inflammatory signaling to protect against lupus nephritis.
Li X, Villanueva V, Jimenez V, Nguyen B, Chauhan NR, Khan SQ, Dorschner JM, Jensen MA, Alzahrani K, Wei H, Cimbaluk DJ, Wei DC, Jolly M, Lopez-Rodriguez D, Pineda SB, Barbosa A, Vazquez-Padron RI, Faridi HM, Reiser J, Niewold TB, Gupta V. Li X, et al. Among authors: khan sq. bioRxiv [Preprint]. 2024 Jul 26:2024.07.26.605143. doi: 10.1101/2024.07.26.605143. bioRxiv. 2024. PMID: 39211173 Free PMC article. Preprint.
Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies.
Panni RZ, Herndon JM, Zuo C, Hegde S, Hogg GD, Knolhoff BL, Breden MA, Li X, Krisnawan VE, Khan SQ, Schwarz JK, Rogers BE, Fields RC, Hawkins WG, Gupta V, DeNardo DG. Panni RZ, et al. Among authors: khan sq. Sci Transl Med. 2019 Jul 3;11(499):eaau9240. doi: 10.1126/scitranslmed.aau9240. Sci Transl Med. 2019. PMID: 31270275 Free PMC article.
133 results