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Page 1
CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus.
Faridi MH, Khan SQ, Zhao W, Lee HW, Altintas MM, Zhang K, Kumar V, Armstrong AR, Carmona-Rivera C, Dorschner JM, Schnaith AM, Li X, Ghodke-Puranik Y, Moore E, Purmalek M, Irizarry-Caro J, Zhang T, Day R, Stoub D, Hoffmann V, Khaliqdina SJ, Bhargava P, Santander AM, Torroella-Kouri M, Issac B, Cimbaluk DJ, Zloza A, Prabhakar R, Deep S, Jolly M, Koh KH, Reichner JS, Bradshaw EM, Chen J, Moita LF, Yuen PS, Li Tsai W, Singh B, Reiser J, Nath SK, Niewold TB, Vazquez-Padron RI, Kaplan MJ, Gupta V. Faridi MH, et al. Among authors: koh kh. J Clin Invest. 2017 Apr 3;127(4):1271-1283. doi: 10.1172/JCI88442. Epub 2017 Mar 6. J Clin Invest. 2017. PMID: 28263189 Free PMC article.
Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1.
Lee HW, Khan SQ, Khaliqdina S, Altintas MM, Grahammer F, Zhao JL, Koh KH, Tardi NJ, Faridi MH, Geraghty T, Cimbaluk DJ, Susztak K, Moita LF, Baltimore D, Tharaux PL, Huber TB, Kretzler M, Bitzer M, Reiser J, Gupta V. Lee HW, et al. Among authors: koh kh. J Biol Chem. 2017 Jan 13;292(2):732-747. doi: 10.1074/jbc.M116.753822. Epub 2016 Dec 2. J Biol Chem. 2017. PMID: 27913625 Free PMC article.
uPAR isoform 2 forms a dimer and induces severe kidney disease in mice.
Wei C, Li J, Adair BD, Zhu K, Cai J, Merchant M, Samelko B, Liao Z, Koh KH, Tardi NJ, Dande RR, Liu S, Ma J, Dibartolo S, Hägele S, Peev V, Hayek SS, Cimbaluk DJ, Tracy M, Klein J, Sever S, Shattil SJ, Arnaout MA, Reiser J. Wei C, et al. Among authors: koh kh. J Clin Invest. 2019 Apr 2;129(5):1946-1959. doi: 10.1172/JCI124793. eCollection 2019 Apr 2. J Clin Invest. 2019. PMID: 30730305 Free PMC article.
A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease.
Hayek SS, Koh KH, Grams ME, Wei C, Ko YA, Li J, Samelko B, Lee H, Dande RR, Lee HW, Hahm E, Peev V, Tracy M, Tardi NJ, Gupta V, Altintas MM, Garborcauskas G, Stojanovic N, Winkler CA, Lipkowitz MS, Tin A, Inker LA, Levey AS, Zeier M, Freedman BI, Kopp JB, Skorecki K, Coresh J, Quyyumi AA, Sever S, Reiser J. Hayek SS, et al. Among authors: koh kh. Nat Med. 2017 Aug;23(8):945-953. doi: 10.1038/nm.4362. Epub 2017 Jun 26. Nat Med. 2017. PMID: 28650456 Free PMC article.
Deiodinase-3 is a thyrostat to regulate podocyte homeostasis.
Agarwal S, Koh KH, Tardi NJ, Chen C, Dande RR, WerneckdeCastro JP, Sudhini YR, Luongo C, Salvatore D, Samelko B, Altintas MM, Mangos S, Bianco A, Reiser J. Agarwal S, et al. Among authors: koh kh. EBioMedicine. 2021 Oct;72:103617. doi: 10.1016/j.ebiom.2021.103617. Epub 2021 Oct 11. EBioMedicine. 2021. PMID: 34649077 Free PMC article.
SuPAR mediates viral response proteinuria by rapidly changing podocyte function.
Wei C, Datta PK, Siegerist F, Li J, Yashwanth S, Koh KH, Kriho NW, Ismail A, Luo S, Fischer T, Amber KT, Cimbaluk D, Landay A, Endlich N, Rappaport J; Michigan Medicine COVID−19 Investigators; Hayek SS, Reiser J. Wei C, et al. Among authors: koh kh. Nat Commun. 2023 Jul 21;14(1):4414. doi: 10.1038/s41467-023-40165-5. Nat Commun. 2023. PMID: 37479685 Free PMC article.
252 results