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Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.
Kamphorst AO, Wieland A, Nasti T, Yang S, Zhang R, Barber DL, Konieczny BT, Daugherty CZ, Koenig L, Yu K, Sica GL, Sharpe AH, Freeman GJ, Blazar BR, Turka LA, Owonikoko TK, Pillai RN, Ramalingam SS, Araki K, Ahmed R. Kamphorst AO, et al. Among authors: araki k. Science. 2017 Mar 31;355(6332):1423-1427. doi: 10.1126/science.aaf0683. Epub 2017 Mar 9. Science. 2017. PMID: 28280249 Free PMC article.
mTOR regulates memory CD8 T-cell differentiation.
Araki K, Turner AP, Shaffer VO, Gangappa S, Keller SA, Bachmann MF, Larsen CP, Ahmed R. Araki K, et al. Nature. 2009 Jul 2;460(7251):108-12. doi: 10.1038/nature08155. Epub 2009 Jun 21. Nature. 2009. PMID: 19543266 Free PMC article.
The role of mTOR in memory CD8 T-cell differentiation.
Araki K, Youngblood B, Ahmed R. Araki K, et al. Immunol Rev. 2010 May;235(1):234-43. doi: 10.1111/j.0105-2896.2010.00898.x. Immunol Rev. 2010. PMID: 20536567 Free PMC article. Review.
1,911 results