Gootwine E - Search Results

1

Gene Augmentation Therapy for a Missense Substitution in the cGMP-Binding Domain of Ovine CNGA3 Gene Restores Vision in Day-Blind Sheep.

Gootwine E, Abu-Siam M, Obolensky A, Rosov A, Honig H, Nitzan T, Shirak A, Ezra-Elia R, Yamin E, Banin E, Averbukh E, Hauswirth WW, Ofri R, Seroussi E. Gootwine E, et al. Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1577-1584. doi: 10.1167/iovs.16-20986. Invest Ophthalmol Vis Sci. 2017. PMID: 28282490 Free PMC article.

2

A mutation in gene CNGA3 is associated with day blindness in sheep.

Reicher S, Seroussi E, Gootwine E. Reicher S, et al. Among authors: gootwine e. Genomics. 2010 Feb;95(2):101-4. doi: 10.1016/j.ygeno.2009.10.003. Epub 2009 Oct 27. Genomics. 2010. PMID: 19874885 Free article.

3

Flicker cone function in normal and day blind sheep: a large animal model for human achromatopsia caused by CNGA3 mutation.

Ezra-Elia R, Banin E, Honig H, Rosov A, Obolensky A, Averbukh E, Hauswirth WW, Gootwine E, Ofri R. Ezra-Elia R, et al. Among authors: gootwine e. Doc Ophthalmol. 2014 Dec;129(3):141-50. doi: 10.1007/s10633-014-9458-6. Epub 2014 Sep 10. Doc Ophthalmol. 2014. PMID: 25204753 Free PMC article.

4

Gene Augmentation Therapy Restores Retinal Function and Visual Behavior in a Sheep Model of CNGA3 Achromatopsia.

Banin E, Gootwine E, Obolensky A, Ezra-Elia R, Ejzenberg A, Zelinger L, Honig H, Rosov A, Yamin E, Sharon D, Averbukh E, Hauswirth WW, Ofri R. Banin E, et al. Among authors: gootwine e. Mol Ther. 2015 Sep;23(9):1423-33. doi: 10.1038/mt.2015.114. Epub 2015 Jun 19. Mol Ther. 2015. PMID: 26087757 Free PMC article.

5

Safety and Efficacy Evaluation of rAAV2tYF-PR1.7-hCNGA3 Vector Delivered by Subretinal Injection in CNGA3 Mutant Achromatopsia Sheep.

Gootwine E, Ofri R, Banin E, Obolensky A, Averbukh E, Ezra-Elia R, Ross M, Honig H, Rosov A, Yamin E, Ye GJ, Knop DR, Robinson PM, Chulay JD, Shearman MS. Gootwine E, et al. Hum Gene Ther Clin Dev. 2017 Jun;28(2):96-107. doi: 10.1089/humc.2017.028. Epub 2017 May 5. Hum Gene Ther Clin Dev. 2017. PMID: 28478700

6

Six Years and Counting: Restoration of Photopic Retinal Function and Visual Behavior Following Gene Augmentation Therapy in a Sheep Model of CNGA3 Achromatopsia.

Ofri R, Averbukh E, Ezra-Elia R, Ross M, Honig H, Obolensky A, Rosov A, Hauswirth WW, Gootwine E, Banin E. Ofri R, et al. Among authors: gootwine e. Hum Gene Ther. 2018 Dec;29(12):1376-1386. doi: 10.1089/hum.2018.076. Epub 2018 Jul 30. Hum Gene Ther. 2018. PMID: 29926749

7

Consecutive unilateral recording of the two eyes affects dark-adapted ERG responses, when compared to simultaneous bilateral recording.

Ross M, Honig H, Ezra-Elia R, Banin E, Obolensky A, Averbukh E, Rosov A, Gootwine E, Ofri R. Ross M, et al. Among authors: gootwine e. Doc Ophthalmol. 2018 Dec;137(3):183-192. doi: 10.1007/s10633-018-9661-y. Epub 2018 Nov 9. Doc Ophthalmol. 2018. PMID: 30411184

8

Naturally-occurring myopia and loss of cone function in a sheep model of achromatopsia.

Ross M, Ofri R, Aizenberg I, Abu-Siam M, Pe'er O, Arad D, Rosov A, Gootwine E, Dvir H, Honig H, Obolensky A, Averbukh E, Banin E, Gantz L. Ross M, et al. Among authors: gootwine e. Sci Rep. 2020 Nov 9;10(1):19314. doi: 10.1038/s41598-020-76205-z. Sci Rep. 2020. PMID: 33168939 Free PMC article.

9

A novel day blindness in sheep: epidemiological, behavioural, electrophysiological and histopathological studies.

Shamir MH, Ofri R, Bor A, Brenner O, Reicher S, Obolensky A, Averbukh E, Banin E, Gootwine E. Shamir MH, et al. Among authors: gootwine e. Vet J. 2010 Aug;185(2):130-7. doi: 10.1016/j.tvjl.2009.05.029. Epub 2009 Jul 9. Vet J. 2010. PMID: 19546015

10

Unveiling genomic regions that underlie differences between Afec-Assaf sheep and its parental Awassi breed.

Seroussi E, Rosov A, Shirak A, Lam A, Gootwine E. Seroussi E, et al. Among authors: gootwine e. Genet Sel Evol. 2017 Feb 10;49(1):19. doi: 10.1186/s12711-017-0296-3. Genet Sel Evol. 2017. PMID: 28187715 Free PMC article.

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